Alp Luachra, an old name for edematous malnutrition

Alp Luachra is a Celtic fairy with a pet newt. It was considered dangerous to fall asleep near a stream. Alp Luachra might climb into the victim’s mouth along with his pet newt. They would live in the stomach and gobble up nutrients while the rest of the accursed person shriveled away. No matter how much the victim would eat they would eventually starve – because Alp Luachra leeches all the nutrition away. I learned of him from my new book, Tarot of the Celtic Fairies. The picture on the Tarot card does resemble edematous malnutrition with a very round belly and thin, starved looking arms and legs. Maybe it does exist outside of the tropics. (The 9 of Cauldrons card from  Tarot of the Celtic Fairies 14)

Kwashiorkor, (that rare tropical form of malnutrition in toddlers weaned from breast feeding too rapidly, and/or from lack of introduction of insects to the diet at the appropriate stage), has been in the news. An insurance billing watch dog group found an increased use of the diagnosis code for kwashiorkor/malnutrition in a group of California hospitals. Prime Healthcare Service’s response to the allegations that a diagnosis of malnutrition was used to increase reimbursement states that the facts were distorted in order to mislead the public and gain concessions. It continues that the “relevant (i.e., where the diagnosis affected reimbursement) malnutrition rate at all Prime Healthcare hospitals was 3.6%,which is much less than the rates referenced in the article. For example, their relevant malnutrition rate at Huntington Beach hospital was 5.3% rather than the 39% reported by California Watch.”

That seems reasonable to me. It continues to review the disturbing prevalence of malnutrition and their screening program that Prime Healthcare hospitals use for improving patient care and decreasing morbidity and mortality rates a nutritional screening for their elderly patients is part of their routine care.

Published studies estimate that up to 15% of ambulatory elderly patients, up to 44% of homebound elderly patients, up to 65% of hospitalized elderly patients, and up to 85% of nursing home patients are malnourished. Hajjar, R.R., Kamel, H.K., Denson, K., Malnutrition In Aging, The Internet Journal of Geriatrics and Gerontology, Volume 1, Number 1 (2004); Chen, C.C-H, Schilling, L.S., Lyder, C.H., A Concept Analysis of Malnutrition In The Elderly, Journal of Advanced Nursing, Volume 36(1) (2001).

** Prime Healthcare sounds like a good place for dietitians to work. A nutrition screening by a Registered Dietitian is vital for quality preventative health care. A multidisciplinary team allows a thorough assessment from multiple viewpoints – a stethoscope or a microscope or a little Celtic sparkle – who knows the health solutions that teamwork can bring. However, I was just reading about albumin on RD411, an information website, today [16]. I learned that low albumin is not considered useful to tell if a patient is malnourished because it is easily influenced by many factors besides dietary protein intake. However, at the same time I learn that it is associated with increased mortality and morbidity – so I am left to assume that  I needn’t consider the elderly person with an albumin of 7 or 8 as ‘malnourished’ but just to consider them at increased risk of morbidity and mortality instead. The recommendation is to continue dietary calculations as normal, but instead of pouring another Health Shake to add to the malabsorbtion mess I would rather consider what is causing the shift in fluid and what might be better absorbed than what we already have been trying.

In research by Yi-Chia Huang et al, the elderly Taiwanese population had an intake range of 573.9 to 3191.9 kcal/day and no association between functional status and intake could be made.  Intake of at least 55 grams protein per day was associated with better function but higher levels of protein intake again could not be correlated to improved status. [7] In cases of malabsorption we can pour in 3000 calories per day and there will be no guarantee that it will be more helpful than 573. It would probably be more harmful than low intake. Anything that passes through the body has to be brought into safe balance with the chemical needs of the intestinal lining. Magnesium is a buffer that is taken from the bones to “fix” over acidic conditions. High protein, dairy and sugar intakes add to acidic conditions and coffee, carbonated beverages, black tea, and fruit juices can be very acidic. For strong bones try choosing an herbal or green tea and pass on the extra large glass of pop or milk and the triple shot of alcohol too probably.

There is controversy over using just the albumin level for a diagnosis of malnutrition and it is true that short term edema – puffiness – will cause low albumin levels while puffy. With less fluid in the blood and more fluid in the spaces between cells and organs there will be less albumin. It is a blood protein that acts a little like a sponge to attract and keep fluid around it but where the fluid goes it is also attracted to follow. Circular paths are the way of nature. The albumin level that remains low for months – rather than during an acute week of an illness – I would strongly consider the possibility that an underlying malnutrition problem is the cause of puffiness and low albumin, the reasons for the initial malnutrition can vary but once the poor absorption starts the problems picks up pace and the body deteriorates from feeding on itself – there isn’t a newt but there is a brain, heart and lungs as long as the fingers, toes and remaining peripherals hold out (reminder Buerger’s vasculitis disease [15]).

One lab test can be supported by other labs and observed signs and symptoms of health or weakness. Several studies have found that assessing frailty factors seems more correlated with a variety of quality of life factors and improved surgical recovery rates than BMI. More than 3 of 5 of the following – unintentional weight loss, weakness, self-reported poor energy, slow walking speed, and low physical activity  was found associated with risks of falls and fractures. Hand grip strength, and calf muscle to fat area, mid arm circumference, sarcopenia were mentioned as measurements of improved muscle mass with improved health status. Sit ups and leg lifts or just a walk in the woods – better muscle mass is associated with longer life.

Based on the sensitivity of the autoimmune gut and my review of kwashiorkor research, I would surmise that a gluten free, lactose free, low calcium to magnesium ratio with an increase in glucosamine and other essential sugars (super starches) and plenty of B vitamins, C, A, zinc, selenium might help the catabolic patient with edema. We need to provide building blocks that readily make a strong glycocalcyx to reduce the leakiness of the intestinal lining.

I am glad that Prime Healthcare has had to stand up for malnourished patient’s rights – the right to a diagnosis that is accurate. An albumin of 7 or 8 is tragic and just because it is from excessive dilution due to malabsorption/mal-retention and not due to lack of protein in the diet – doesn’t mean it isn’t leading to cell starvation. Just because we don’t quite understand edematous malnutrition and don’t seem to know how to stop it, doesn’t mean that it doesn’t exist and isn’t killing people in a very costly and agonizingly slow way.

Names matter and the tropics and kwashiorkor is simply where the problem was studied most. Edematous malnutrition is a better name for the condition in my opinion than protein calorie malnutrition. Over the long term edema means that the cells aren’t being well fed or well detoxified. During edema the movement of fluid is reduced and the movement of nutrients and toxins is slowed. Over the long term edema leads to dysfunction and malnourishment. If the fluid in our toilets backed up regularly we would expect the plumber to repair it not just measure the dysfunction. Puffy abdomen and ankles = overflowing waste = better call a doctor on the Prime Healthcare team in case malnutrition is involved (and remember to ask for a referral to a Registered Dietitian); maybe repair is still in the future but recognition is at least a first step.

Kwashiorkor occurs on the same diet as marasmus malnutrition but the children have different metabolic reactions. Recent infection may be associated with the kwashiorkor susceptible population. Their intestinal lining lacked glucosamine and excess fluid movement both directions was the result. An enzyme deficiency for the conversion of glucose or galactose into glucosamine seemed to be a significant difference between the two groups of children and aldosterone levels were also abnormal in the kwashiorkor children but not the maramus group. Edematous malnutrition exists outside of the tropics.
Glucosamine supplements may be crucial for heart disease and other leaky membrane problems (dementia). Zinc and selenium are low in heart disease and B6 and all of the B vitamins are essential for cell growth and energy demands. Vitamin C is also depleted rapidly. Our “health supplement shakes” and complete feeding formulas are not based on ratios that the critically ill can tolerate – they are more harmful than helpful. We need research and development of an isotonic formula with high levels of beneficial nutrients and low levels of a few things that add to the body burden .

In the meantime more magnesium, B complex, zinc, selenium, iodine, glucosamine, taurine, vitamin C, and beta carotene rich dark green and deep orange fruit and vegetables may be helpful to the chronically ill and obese. Mushrooms, aloe vera, fenugreek, slippery elm powder and ginger also have essential sugars – super fiber for building a strong glycocalyx. The intestinal lining is an organ that protects and nourishes our bodies for miles – literally – do we want junk food littering the way or a strong yet fluid, free-form matrix of super starches, trace mineral ions lighting up the place and plenty of strong white blood cells patrolling for trouble.  Cancer wouldn’t stand a chance – or at least reduced chance.

***11-7-11 BTW I figured out what’s happening with the leaky membrane problem – its complicated – call me or read the [bazillion words, “Cantaloupe, listeria, and sea squirts, oh my,” Oct. 5, 2011]

__________________________________________________________________________

 /Disclosure: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./
  1. Olubukola O. Nafiu et al., “The Association of Body Mass Index to Postoperative Outcomes in Elderly Vascular Surgery Patients: A Reverse J-Curve Phenomenon,” Anesthesia & Analgesia 112, no. 1 (January 1, 2011): 23 -29.
  2. Ian M Chapman, “Obesity paradox during aging,” Interdisciplinary Topics in Gerontology 37 (2010): 20-36.
  3. S L Miller and R R Wolfe, “The danger of weight loss in the elderly,” The Journal of Nutrition, Health & Aging 12, no. 7 (September 2008): 487-491.
  4. Ian Janssen, “Morbidity and mortality risk associated with an overweight BMI in older men and women,” Obesity (Silver Spring, Md.) 15, no. 7 (July 2007): 1827-1840.
  5. Kristine E. Ensrud et al., “Frailty and Risk of Falls, Fracture, and Mortality in Older Women: The Study of Osteoporotic Fractures,” The Journals of Gerontology Series A: Biological Sciences and Medical Sciences 62, no. 7 (July 1, 2007): 744 -751.
  6. Meei-Fang Lou et al., “Nutritional status and health outcomes for older people with dementia living in institutions,” Journal of Advanced Nursing 60, no. 5 (December 2007): 470-477.
  7. Yi-Chia Huang et al., “Nutritional Status of Functionally Dependent and Nonfunctionally Dependent Elderly in Taiwan,” J Am Coll Nutr 20, no. 2 (April 1, 2001): 135-142.  (free article)
  8. Matteo Cesari et al., “Frailty syndrome and skeletal muscle: results from the Invecchiare in Chianti study,” The American journal of clinical nutrition 83, no. 5 (May 2006): 1142-1148.  (free article)
  9. H K Vincent, K R Vincent, and K M Lamb, “Obesity and mobility disability in the older adult,” Obesity Reviews: An Official Journal of the International Association for the Study of Obesity 11, no. 8 (August 2010): 568-579.
  10. Heppenstall, et al, “Frailty: dominos or deliberation?,” N Z Med J. 2009 Jul 24;122(1299):42-53. http://www.nzma.org.nz/journal/122-1299/3710/.
  11. Fred Chau-Yang Ko, “The clinical care of frail, older adults,” Clinics in Geriatric Medicine 27, no. 1 (February 2011): 89-100.
  12. Stephane M Schneider et al., “Lack of adaptation to severe malnutrition in elderly patients,” Clinical Nutrition (Edinburgh, Scotland) 21, no. 6 (December 2002): 499-504.
  13. Lilian Liang et al., “Nutritional issues in older adults with wounds in a clinical setting” 1: 63-71.
  14. McElroy, Mark, Tarot of the Celtic Fairies, artwork by Eldar Minibaev, (2010, Lo Scarabeo, Via Cigna 110 – 10155 – Torino- Italy _www.loscarabeo.com_ (I hope this will be viewed as a brief extract and recommendation rather than copyright infringement.  I find Tarot cards a meditative cognitive therapy aid – solitaire for the brain.)
  15. http://www.hopkinsvasculitis.org/types-vasculitis/buergers-disease/ ***I discussed it in my article Vasculitis – Withering from Within.The main cause of this type is smoking and the best treatment is to quit smoking. Smoking depletes oxygen and antioxidants and magnesium – malnourishment from within – second best to quitting smoking would be of course to replenish with extra vitamin C and magnesium supplements and foods and some oxygen would help also vitamin A foods – supplements have not been helpful but the food has helped . . . carrots, peaches, sweet potatoes, tomatoes, broccoli and V8, mangos, apricots and cantalope.
  16. http://www.rd411.com/index.php?option=com_content&view=article&id=393:albumin-as-an-indicator-of-nutritional-status&catid=105:professional-refreshers&Itemid=400
  17. see my previous blogs Angelina please don’t risk the knife, and We are what we eat, for more Bibliography on kwashiorkor, insects and perimenopause.
  18. see my previous blogs on the glycocalyx and Electrolytes R Us, for more on leaky membranes and hydration.
  19. http://www.highbeam.com/doc/1G1-250812435.html . “Prime Healthcare Services Review of State Health Data Confirms Normal Malnutrition Rates Among Its Medicare Patients; Recent Studies Debunked.(Clinical report).” PR Newswire. PR Newswire Association LLC. 2011. HighBeam Research. 9 Apr. 2011 http://www.highbeam.com.

From a different list of reading:
7. Yi-Chia Huang et al., “Nutritional Status of Functionally Dependent and Nonfunctionally Dependent Elderly in Taiwan,” J Am Coll Nutr 20, no. 2 (April 1, 2001): 135-142.  (free article)

Excerpt from Conclusions section:
“There were approximately 36% of functionally dependent subjects who consumed energy less than 75% of the Taiwan RDNA in our study. The elderly with functional dependence might have more difficulties in accessing food. However, we could not find an association between energy intake and functional status. This might be due to large variations of energy intake among individuals ranging from 573.9 to 3191.9 kcal/day.
Consistent with Payette and Gray-Donald [24], the elderly had sufficient mean protein intake, but these authors’ association between protein intake and serum albumin concentration was not found. Morgan et al. [6], however, indicated a positive relationship between protein intake and serum albumin concentrations. It is worth noting that the association was valid only up to protein intake of 55 g/day. Since our subjects had a varied protein intake ranging from 23 g/day to 122 g/day and half of the subjects had a protein intake .55 g/day, the dietary protein intake might no longer have an effect on serum albumin concentration. Another possibility was that chronic conditions play a determinant role in affecting the albumin concentration.”

***Note on vitamin D – The chronically ill may have depressed 25-D levels because they have elevated 1,25 D levels resulting in more than enough of the active hormone for preventing fractures even though the vitamin level seems insufficient for the average person.

The enzyme to activate the vitamin to the steroidal hormone is made by white blood cells as part of the stress/inflammation response and in some cancer cell strains. An active D level above 45 means the bones are losing calcium stores. My five year 1,25-D average, while actively avoiding vitamin D foods, supplements and much time in the sun, was 59 pg/ml and my five year average 25-D was 20 ng/ml. The range was 51-71 pg/ml, 1-25-D and 8.0-26.7 ng/ml for 25D. Ex: 3-31-2009 25-D of 9.0 and 1-25D of 53 pg/ml. If I spend a day on the beach I am hurting two days later from the calcium that is drawn out of the bones – muscle spasms, fatigue and irritability symptoms primarily for me but ringing in the ears and a twitching eyelid have been reduced with magnesium. B vitamins and zinc tend to be involved to – magnesium rich foods would provide those as well as iron and iodine only if it was grown in iodine rich soil.

Kwashiorkor Bibliography

  1. http://www.ajcn.org/content/89/2/592.long ***Reduced production of sulfated glycosaminoglycans occurs in Zambian  children with kwashiorkor but not marasmus also good –
  2.  http://www.icmr.nic.in/ijmr/2009/November/1128.pdf  Tahmeed Ahmed, Sabuktagin Rahman and Alejandro Cravioto, Oedematous malnutrition,  Indian J Med Res 130, November 2009, pp 651-654
  3.  http://www.pe.com/localnews/stories/PE_News_Local_D_malnutrition20.27e2afa.htmlWilliams, L., Jewett, C., and Doi, S. K., Hospital chain, under scrutiny, reports rare illness (The Press Enterprise Local News)
  4. http://www.pe.com/localnews/opinion/editorials/stories/PE_OpEd_Opinion_D_op_27_ed_primehealth.1816fbc.html  Shady billing? (The Press Enterprise)
  5. http://www.sacbee.com/2011/02/20/v-print/3414850/medicare-billed-for-exotic-illness.html
  6. Prime Healthcare Should Be Denied New Hospital Licenses Until Federal, State Investigations into Extraordinarily High Septicemia, Malnutrition Rates and Risk to Patients are Complete.Business Wire. Business Wire. 2011. HighBeam Research.
  7. http://online.wsj.com/article/SB10001424052748703293204576106072340020728.html  Marcel Dicke, Arnold Van Huis are professors of entomology at Wageningen University in the Netherlands.  (2-19-11, The Wall Street Journal, pC3)  The Six-Legged Meat of the Future
  8. http://onlinelibrary.wiley.com/doi/10.1111/j.1525-139X.2010.00705.x/abstractEffect of Diabetes Mellitus on Protein–Energy Wasting and Protein Wasting in End-Stage Renal Disease, Nazanin Noori1, Joel D. Kopple1,2Article first  published online:13 APR 2010DOI: 10.1111/j.1525-139X.2010.00705.x
  9. http://www.ncbi.nlm.nih.gov/pubmed/19121473  Semin Nephrol. 2009 Jan;29(1):39-49. Causes and prevention of protein-energy wasting in chronic kidney failure. Dukkipati R, Kopple JD. Division of Nephrology and Hypertension, Los Angeles Biomedical  Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90509, USA.
  10. http://www.ncbi.nlm.nih.gov/pubmed/19121477 Semin Nephrol. 2009 Jan;29(1):75-84. Nutrition support for the chronically wasted or acutely catabolic chronic kidney disease patient.Ikizler  TA.Department of Medicine, Division of Nephrology, Vanderbilt University School of  Medicine,Nashville, TN 37232-2372, USA.
11. http://www.ncbi.nlm.nih.gov/pubmed/16129200Am J Kidney Dis. 2005 Sep;46(3):387-405. Multinutrient oral  supplements and tube feeding in maintenance dialysis: a systematic review and meta-  analysis. StrattonRJ, Bircher G, Fouque D, Stenvinkel P, de Mutsert R, Engfer M, Elia  M.Instituteof Human Nutrition, University of Southampton, UK.

12.  http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891019/?tool=pubmed New Insights into the Role of Anabolic Interventions in Dialysis Patients with Protein Energy Wasting Jie Dong and T. Alp Ikizler1 Curr Opin Nephrol Hypertens. Curr Opin Nephrol Hypertens. 2009 November; 18(6): 469–475.doi: 10.1097/MNH.0b013e3283 31489d.

 “Economic Implications of Nutritional interventions It is also important to assess the impact of nutritional supplements not only in terms of changes in nutritional parameters, but to extrapolate these observations to potential improvements in hospitalization, mortality, and cost-effectiveness. In a recent study, Lacson et al showed that a hypothetical increase in serum albumin concentration in the order of 2 g/L in 50%  of the United States dialysis population would be associated with  projections of approximately 1400 lives saved, approximately 6000 hospitalizations  averted, and approximately $36 million in Medicare cost savings resulting  from a reduction of approximately 20,000 hospital days over one year[68]. This is a reasonable estimation since 2 g/L increase in serum albumin is the average improvement reported in most nutritional intervention studies.”

***The above paper is suggesting that giving them growth hormones  and other anabolic steroids along with protein will help them to stop catabolizing and start building albumin. They have had success with the strategy, but wouldn’t magnesium plus protein (ideally combined within the same magnesium foods) be cheaper than hormones and protein?

We are what we eat.

The cattle are as good as the pasture in which they graze.
-Ethiopian proverb
We can build better bodies and better babies with normal healthy food. Tweaking ratios in our supplements and formulas would make it easier to get what we need but in the mean time moderate use of typical foods can feed us well. Babies would benefit from more human milk use whether from individual mothers or donated milk banks. It would help infant’s neuro-development and might help prevent some colic and sleepless nights. If infant formula is necessary than an occasional quarter teaspoon of Milk of Magnesia might prevent problems from the slightly high calcium/magnesium ratio (cow’s milk is quite a bit higher in calcium and protein than the modified formula product and is not suitable for use with young infants).
The levels of a  few nutrients in breast milk can be adversely affected by diet or health and magnesium is one of them. The average is around 30 mg/liter but the level can drop to the low 20’s and does in malnourished populations and teen moms and it can be elevated around 45 mg/liter in diabetic moms.
Young women, aka teen moms, are also more at risk for preeclampsia, as are mothers of twins. Both of these groups have increased nutrient needs – they are eating for baby plus more. These two sub-populations are linked with malnourished women in third world country studies by the unusually low magnesium levels in their breast milk. The high levels in the diabetic women suggests to me that the cell membranes are allowing too much out – that they have become leaky somehow.
We need more vegetables, nuts, seeds, and beans for magnesium but they also give us protein and fiber. The healthy starches are necessary for a strong protective intestinal lining. White blood cells patrol and pick off allergens, infection and other information and send it up to lymph nodes. At the lymph nodes more specialized work takes place to identify the foreign proteins and replicate defensive antibodies if needed. Nature provided us this natural oral vaccination method but healthy foods are necessary to build blood cells and make the glycocalyx jelly lining around the intestinal folds.

The United Kingdom recently released the nutrition recommendation to eat less red meat. Americans were told to eat less red meat a while ago . . . and we did, however we started eating more chicken, and cheese intake also increased — from a USDA report on 1909 to 2000 US nutrient intake. [2 -Table 32] Between 1970 and 2000 red meat use dropped fifteen percent! But chicken use increased 80 percent and cheese 150 percent. Chicken in the form of nuggets and other breaded and fried forms has become a staple that had been a special occasion food . The hidden added oil of fried chickend and the saturated fats of the cheese made “eat less red meat” a nutrition recommendation that worked and failed. We are eating less red meat than we used to in America but we are eating more cheese and chicken .

I would like to encourage a positive spin of less red meat and more beans, nuts and seeds for a protein source that also provides healthy fiber and many other trace nutrients. Having a variety of types of foods daily or throughout the week will generally provide more trace nutrients. We need hundreds of types of chemical compounds, not just ten or twenty vitamins and minerals. A few trace nutrients are considered essential for our health because our bodies can not create them out of other simpler chemicals. However other trace chemicals may become more important to consume in the diet or take as supplements if a person has a problem with some of the conversion steps necessary to make important enzymes or proteins or other more complex molecules. Eating liver and onions once a month may provide a boost to our health because it provides fully formed enzymes that can be more easily reassembled by the body after they are broken down and absorbed during digestion.

Using a variety of protein sources throughout the week or mixed in the meal may provide more variety of some of the more unusual types of essential sugars. A rich beef stock made from marrow rich bones will yield glucosamine, one of the essential sugars or glyco-nutrients. Many people use it as a supplement for arthritis pain. It can have a positive effect after taking it for a few weeks. Glucosamine is found in the synovial fluid that cushions the area between the bones of the knee and other joints in the body. A supplement recommendation is 1500 mg/day. [Synovial and plasma glucosamine concentrations in osteoarthritic patients following oral crystalline glucosamine sulphate at therapeutic dose, S. Persiani, Ph.D, et. al., Osteoarthritis and Cartilage, Volume 15, Issue 7, July 2007, Pages 764–772]
Supplements may be from a shellfish source as it is frequently derived from crustacean shells so people with shellfish allergies should look for a vegetarian source.
Glucosamine is also found in the chitin of insects. The use of insects in the diet may have helped prevent kwashiokor in young children in tropical regions. The intestinal lining in some individuals, possibly those who had a recent infection, seems to malfunction in the ability to convert other sugars into glucosamine. The use of a rich broth from a bone stock might suit more people’s taste than insects. Although there are chefs presenting some appetizing dishes. . . . citations to follow when I am more awake.
Moderate use of dairy products like cheese, milk, yogurt and other calcium rich foods would benefit bone health without sacrificing magnsium absorption. Two to three dairy servings per day would provide adequate calcium. Supplements are not generally needed.
The food pyramid and http://www.mypyramid.gov is a nice start but I tend to recommend:
    • a bit less grains – swap some starchy root vegetables for the carbohydrate calories,
    • and a bit more vegetables -AICR – recommends 5-9 veg and fruit per day as anticancer medicine.
    • Juice is concentrated and limiting to 4-6 oz/day is healthy – especially for small bodies.
    • A bit less meat and dairy groups and use the calories for nuts, beans, and seeds.

/Disclosure: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./

*2015, edit, I’m not sure why I included this chart in 2011 but I’m leaving it here for now.

http://www.nal.usda.gov/fnic/foodcomp/search/             nutrient data base

NBD #
Food
Unit
kcal
protein
fat
Calcium
Magns.
Vit D IU
Vit A IU
01211
Whole milk no added A or D
1 cup
149
7.67 gr
7.98 gr
276 mg
24 mg
5 IU
395 IU
01107
Human milk, mature
1 cup
172
2.53 gr
10.77 gr
79 mg
7 mg
7 IU
522 IU
03850
Infant Formula, similac
100 gr x 2.43 = 1 cup
158
3.3 gr
8.62 gr
124 mg
10 mg
95 IU
479 IU

**Note that the example infant formula is fortified with vitamin D at 13.6 times the amount of human milk and 19 times the amount in cow’s milk. There are more nutrients but the blog is narrow.

1.      http://online.wsj.com/article/SB10001424052748703293204576106072340020728.html  Marcel Dicke, Arnold Van Huis are professors of entomology at Wageningen University in the Netherlands.  (2-19-11, The Wall Street Journal, pC3)  The Six-Legged Meat of the Future, Insects are nutritious and easy to raise without harming the environment. They also have a nice nutty taste

2. http://www.cnpp.usda.gov/publications/foodsupply/foodsupply1909-2000.pdf Gerrior, S., Bente, L., & Hiza, H. (2004). Nutrient Content of the U.S. Food
Supply, 1909-2000. (Home Economics Research Report No. 56). U.S. Department of Agriculture,
Center for Nutrition Policy and Promotion.
http://onlinelibrary.wiley.com/doi/10.1111/j.1525-139X.2010.00705.x/abstract
 Effect of Diabetes Mellitus on Protein–Energy Wasting and Protein Wasting in End-Stage Renal Disease, Nazanin Noori1, Joel D. Kopple1,2Article first  published online:13 APR 2010DOI: 10.1111/j.1525-139X.2010.00705.x

http://www.ncbi.nlm.nih.gov/pubmed/19121473  Semin Nephrol. 2009 Jan;29(1):39-49. Causes and prevention of protein-energy wasting in chronic kidney failure. Dukkipati R, Kopple JD. Division of Nephrology and Hypertension, Los Angeles Biomedical  Research Institute at Harbor-UCLA Medical Center, Torrance, CA 90509, USA.
 http://www.ncbi.nlm.nih.gov/pubmed/19121477 Semin Nephrol. 2009 Jan;29(1):75-84. Nutrition support for the chronically wasted or acutely catabolic chronic kidney disease patient.
Ikizler  TA.Department of Medicine, Division of Nephrology, Vanderbilt University School of  Medicine,Nashville, TN 37232-2372, USA.

http://www.ncbi.nlm.nih.gov/pubmed/16129200Am J Kidney Dis. 2005 Sep;46(3):387-405. Multinutrient oral  supplements and tube feeding in maintenance dialysis: a systematic review and meta-  analysis. StrattonRJ, Bircher G, Fouque D, Stenvinkel P, de Mutsert R, Engfer M, Elia  M.Instituteof Human Nutrition, University of Southampton, UK.
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2891019/?tool=pubmed New Insights into the Role of Anabolic Interventions in Dialysis Patients with Protein Energy Wasting Jie Dong and T. Alp Ikizler1 Curr Opin Nephrol Hypertens. Curr Opin Nephrol Hypertens. 2009 November; 18(6): 469–475.doi: 10.1097/MNH.0b013e3283 31489d.
 “Economic Implications of Nutritional interventions It is also important to assess the impact of nutritional supplements not only in terms of changes in nutritional parameters, but to extrapolate these observations to potential improvements in hospitalization, mortality, and cost-effectiveness. In a recent study, Lacson et al showed that a hypothetical increase in serum albumin concentration in the order of 2 g/L in 50%  of the United States dialysis population would be associated with  projections of approximately 1400 lives saved, approximately 6000 hospitalizations  averted, and approximately $36 million in Medicare cost savings resulting  from a reduction of approximately 20,000 hospital days over one year[68]. This is a reasonable estimation since 2 g/L increase in serum albumin is the average improvement reported in most nutritional intervention studies.”

***The above paper is suggesting that giving them growth hormones  and other anabolic steroids along with protein will help them to stop catabolizing. They have had success with the strategy, but wouldn’t magnesium plus protein (ideally magnesium foods) be cheaper than hormones and protein.

Dietitian Recommends less Vitamin D and Calcium

We can cure the epidemic of ill health and obesity that has seized our nation and the world. The food supply is low on some important nutrients and has too much focus on calcium. Calcium is important but health is built on a variety of essential nutrients, and clean air and water of course.
We can have health if we seek to rebuild instead of hunt for a disease to name and for a magic bullet cure. There will always be a need for acute care but we are overloading the medical system with chronic degenerative disease. Chemotherapy kills and so do corticosteroids. They are powerful drugs that are aimed at the disease but our bodies get in the way. Food that nourishes with a full range of essential nutrients in forms that can be absorbed and used can help us heal ourselves from within.
We are designed to fight cancer and to rebuild organs using our own stem cells and white blood cells but we can only do that if they are working right. White blood cells protect us by patrolling for old, pre-cancerous or infected cells. The bad cells can be mercy-killed in a process called apoptosis. We grow new skin cells every day and new intestinal cells weekly. New cells of whatever type we need can be rebuilt from our own stem cells. Any organ can be ours for the making – if we have the essential nutrients in our food supply in a mixture that we can absorb.
Our food supply isn’t providing us with the variety of nutrients that we need, in ratios that we can absorb well. Our nutrient guidelines were developed in the 1940’s to help make K-rations that could keep our soldiers strong and healthy under conditions of war.  The original work has been reviewed and modified by the Institute of Medicine. The calcium guidelines were increased in 1997 and while they have been reviewed they haven’t been changed since. The increase was based on an estimation of how much calcium might be needed for better bone absorption.
Do we have stronger bones now as a nation then we did in 1996? That is a simple question with a simple answer – no.Our nation’s diet was changed in 1997 and since then chronic illness, obesity and osteoporosis rates have been expanding quicker than our budgets or belts.
We can’t grow strong bones out of excessive calcium and vitamin D supplements. Bones do require some vitamin D and calcium but we also need magnesium, strontium, vitamin K, and water to name a few essential nutrients.
Calcium is being consumed at levels that our bodies are not able to excrete. The kidneys actively save calcium and use magnesium to remove acidic wastes and some of the excess calcium. Diuretics and alcohol use also increase magnesium losses. Magnesium is lost in sweat but many brands of electrolyte beverages don’t contain it. Our food supply is low in magnesium and high in calcium from dairy products, fortified foods, and supplements.
The dairy products available in our U.S. food supply in the year 2007 provided 716 milligrams of calcium in just 351 calories of cheese and milk per day. Many people eat more than 351 calories of dairy products daily. On average we are consuming more cheese and less milk than we did prior to 1970. Cheese is a more concentrated source of fat and calcium than liquid milk.
Toddlers (n=925) usual intakes from food, beverages, and supplements as reported in FITS 2008 provided on average 892 mg/day of calcium and 160 mg/day of magnesium.
The abnormal vitamin D levels have been misunderstood. Low lab values are linked to ill health and obesity but more of the vitamin won’t fix the underlying problem. The mega-dose is a short term fix but not a long term cure for chronic illness and cancer. It is considered safe for everyone but it is only safe for those with healthy kidney control over the activation of vitamin D to hormone D. High levels of the active hormone D can cause health problems to worsen over time, adding to chronic degeneration.
Vitamin D has two forms and two lab tests of interest, and one test is more expensive. The cheap lab test for 25 hydroxy D (Dᴣ), is what most of the research is based on. It is the inactive form of the vitamin and is available as a supplement. It is considered safe at higher doses because it is assumed that all people, not just healthy people, have very good kidney control over the activation of the vitamin to the hormone. The enzyme needed for activation to 1,25 dihydroxy D is being produced uncontrollably by inflammatory white blood cells and it has been shown to be produced by some cancer cell strains as well.
We are not deficient in vitamin D and haven’t been since milk fortification was begun. The average American’s serum 25-D levels were normal, above 20 ng/ml and Canadian’s had average levels around 24 ng/ml, also normal, from a 2009 Institute of Medicine report. An increased risk of fractures has not been observed at these levels. [4]
Lack of sunlight is not a problem either, according to the research by Dr. James Norman. He has put together a database of over 10,000 patients with hyper-para-thyroidism from around the world who live under a wide range of sunlight conditions. Their vitamin 25-D levels average 19.4 ng/ml, but their active hormone, 1-25 D levels and calcium levels are very high no matter where they live. As soon as their para-thyroid tumor is removed their bodies’ 25-D and 1-25 D balance normalize, no matter where they live.
Dr. Norman, does not recommend supplementing with vitamin D. The supplements push the patient’s lab values for 1-25 D and calcium even higher. He has multiple case examples where stroke or sudden illness occurred after vitamin D supplementation was begun by the patient’s endocrinologist. His seminar about it is on Youtube, listed under ParaThyroid TV, and is posted on my webpage.
I recently started working at an assisted living facility and many of the residents were started on high doses of vitamin D by their individual doctors about a year ago when this research was first getting popular. I read charts cover to cover – and I saw their quality of life deteriorate, their pain levels increase, and worsening of their weakness, cardiac symptoms and dementia, and one death. High doses of vitamin D may not be safe for unhealthy people.
Our public health initiatives have been successful at preventing rickets in the majority; we already won the battle against vitamin D deficiency. Many foods are now fortified with vitamin D not just milk. I met about 4000 babies in fifteen years as a WIC dietitian and only one showed early symptoms of rickets. He was exclusively breast fed and he and his mother both had severe milk protein allergies. They both took to sardines which are an excellent natural source of vitamin D, and supplements were never even needed for the little boy.
We are not vitamin D deficient but we do have a sub-population of chronically ill and obese people with depressed levels of the inactive form of the vitamin. The inactive vitamin Dᴣ is being activated at an unlimited rate in some cancer cells and by white blood cells in wound and inflammatory conditions, resulting in elevated levels of the active hormone form.
Increased levels of the active hormone cause movement of calcium and magnesium out of the bone which eventually leads to osteoporosis of the bone and calcification of everything else. It increases intestinal absorption of calcium and it can increase levels of cortisol, the stress hormone. [39] Too much cortisol can increase abdominal weight gain but it also acts like corticosteroid drugs on the immune system.
Activated hormone D leads to increased cortisol and a short term reduction in inflammatory symptoms because it kills off the overactive white blood cells. However it also kills off the healthy ones. Mega doses of vitamin D are being used in a way similar to corticosteroids. Ultimately the immune system is functioning even worse. The current increase in allergic sensitivities to foods like gluten and peanut butter is due to the over active white blood cells. If we kill off the white blood cells then we won’t get the allergic symptoms as bad but we may get more colds, skin infections, and other illnesses.
Mega-dosing with vitamin D is like paying for Prednisone, if we’re sick and for an expensive cholesterol supplement if we’re healthy. 
Vitamin D is actually a very powerful steroidal hormone based on cholesterol. The average American is making enough vitamin D from their stored cholesterol. Vitamin D is an expensive cholesterol supplement if you don’t need it.[1]  If you are worried about whether you need a supplement or currently are supplementing with vitamin D, then ask your medical provider for both lab tests, cheap and expensive, 25 hydroxy D and 1, 25 dihydroxy D.  The good news is that the combined test result comparison will serve as a biomarker to show who does have chronic inflammatory conditions – proving that fibromyalgia isn’t all in our heads.
Low levels of 25-D combined with high levels of 1,25 D is an abnormal balance that is not seen in the healthy person with good kidney control.It occurs due to the increased production of the activating enzyme in the cancer cells or infected cells. Autoimmune disease may be due to a variety of chronic infections that are not readily identifiable by today’s standard lab tests.
Excessive levels of the active vitamin D cause the bone to lose calcium and magnesium. Too much calcium can cause muscle cramps, increase pain, and can cause anxiety, irritability and headaches.
We need less calcium then we are getting on average and more magnesium. If we limit our intake to 800 mg calcium we should absorb magnesium better, but we still need about twice as much magnesium as we are currently getting. Nuts, beans, seeds and greens are all excellent sources of magnesium and so is chocolate. Just two and a half dairy servings per day, about what is recommended already, would provide adequate calcium for strong bones without overloading our intestines. Too much calcium is causing magnesium to be poorly absorbed in the intestines and to be wasted in urinary losses.
Magnesium blocks calcium channels in cell membranes and would protect the brain cells from being over-flooded with calcium and being overworked to the point of cell death. The over-excitation of the brain cells causes anxiety and irritability and may be underlying the increase in rates of bullying and violence. PMS is another name for magnesium deficiency that is associated with excessive irritiability and chocolate cravings (a good source of magnesium).
Magnesium provides power inside of the cell – fatigue is a common symptom of magnesium deficiency. Anemia and edema are early symptoms of magnesium deficiency. It is essential for the growth of mature red and white blood cells in bone marrow. It is used by over 300 enzymes and it is essential for apoptosis – the mercy killing of infected and precancerous cells. Hypertension and increased serum cholesterol and insulin are also symptoms. If I were writing the books, then Metabolic Syndrome would be called magnesium deficiency and so would pre-eclampsia.
We can heal ourselves, if we learn how to feed ourselves better and repair the food supply and nutrient guidelines.I recommend stopping the push to supplement with vitamin D and calcium and instead I would encourage trying the DASH diet plan. It was a primary education tool that I used successfully to prevent pre-eclampsia reoccurrence in high risk women. The DASH diet provides a good supply of magnesium from the Bean, Nut and Seed food group. The plan has been found helpful for weight loss as well as reducing hypertension.
I propose ten steps for turning around our epidemic of chronic illness and obesity
  1.  Look for health in Food First, treating symptoms does not restore function.
  2. Increase Magnesium in water and other electrolyte beverages. Softened water adds salt to our daily intake and sucks magnesium from our bones.
  3.  Increase magnesium rich foods. They also give us fiber that builds a healthy glycocalyx lining and stronger immune system. Beans, nuts, seeds, greens, whole grains and chocolate are good sources and there is a little in everything else.
  4. Sub-populations need to be identified and informed about their individual nutrient needs, whether increased or decreased from the average person’s to promote optimal health and quality of life.
  5. Poor intestinal absorption of magnesium is part of the problem. We can deliver nutrients from other directions. Skin lotions and Epsom salt (MgSO4) baths are low budget, low risk and very effective methods. [35, 36, 37]
  6.  Nutrients can be delivered by inhalation in an aerosolized  form that would be safer than intravenous magnesium use. [30, 31]
  7.  Limit calcium intake – more is not better. We will retain more when we consume less. The research on strong bones and calcium supplements were for people whose native diet averaged 300 mg calcium per day – not our current RDA of 1000 mg.
  8. Don’t worry about D deficiency and if you are worried then ask for both tests, the inactive and active form of the most powerful hormone in our body.
  9. Ask your government representatives to support food labeling reform. Neotame and free amino acids may be causing migraines, seizures and lead to dementia.
  10. We need our Nutrient Guidelines – the math – checked by a multi-disciplinary team of scientists who use the numbers – food scientists, dietitians, and biochemists should be involved. The math makes our infant formulas and cafeteria menus and when it is wrong then we all suffer.
All nutrients are equally essential. Currently our food supply and health care messages are over-loaded with calcium and vitamin D and it is hurting us. Draining the magnesium from our bones is draining the energy and fluid from our cells and leaves us puffy and pale from anemia. Without magnesium we can’t grow proper blood cells and without healthy white blood cells we can’t protect ourselves from infections and we can’t breakdown decaying, pre-cancerous cells for normal recycling.
Cancer occurs from old cells mutating. Healthy white blood cells can kill the active cancer too. The Linus Pauling Institute successfully treats tumors with high doses of vitamin C. The Gerson Clinic successfully uses a raw foods approach and detoxification with coffee enemas Not too pretty sounding but chemotherapy isn’t pretty either. Why do we continue to hurt people with harsh chemicals when nature gave us what we need in whole foods and the potent herbs and spices. Cinnamon, oregano and rosemary have shown promise in chronic illness. Spice up your lives and enjoy.
Our bodies can do it, we just have to feed ourselves an absorbable balance of a wide variety of essential nutrients.

See Bibliography on the page with this title. I will continue to add to it as I get it organized .

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. Please see an individual health care professional for individualized health care services. If you have questions or comments please contact me at: jenniferdepew@jenniferdepew.com

Hypothyroid or Iodine Deficient ?

Both is the answer or kind-of is the answer to the question in the title. I realize I never answered it directly in the post or may not have explained it clearly. We may have the RDA, the Recommended Daily Allowance, of iodine in a supplement or fortified products each day — but if the environment and diet are also providing the chemically similar minerals bromide, perchlorate (chloride), and fluoride then the body may be making thyroid hormone with the atoms of bromide, chloride and fluoride instead of with atoms of iodine and a lab test might show the presence of thyroid hormone but that lab test wouldn’t be testing specifically for the presence of iodine.
     Thyroid hormone might be present that contained bromide, chloride, or fluoride, or a combination, but it wouldn’t actually function within the energy pathways in the body and symptoms of tiredness and other symptoms of hypothyroidism.  A very large dose of iodine taken for one month can help the body replace the wrong atoms in the thyroid hormone with atoms of iodine. The presence of bromide, chloride and fluoride may be involved in risk for autoimmune thyroid disease and cancer of the thyroid or other endocrine glands. More is included on these topics later in this post. It can also help resolve the pain of fibrocystic breast disease, that topic isn’t included in this post but I did find it helpful for resolving that condition for me, and it hasn’t returned. I had symptoms of it for years and the standard answer is along the lines of “we don’t know,” – well I know that for me my condition resolved after taking a large dose of iodine for one month and then a smaller but still larger than RDA dose for several years — but I didn’t know about or forgot the selenium and ran into hyperthyroid problems, more on that –>
*This updated post is not about being fat or thin, or “body-shaming,” inner beauty has nothing to do with size, however good health can have to do with size.  Mood and skill in social settings can also be affected by size.  Information about cancer is included in this post because a problem with iodine deficiency can increase risk for cancer.
     The commonly used treatment for hypothyroidism within the current medical community is simply replacement of the thyroid hormone which is not addressing iodine deficiency for the thyroid gland or for the rest of the endocrine glands and the rest of the body. The thyroid organ can preferentially take up iodine when there is a limited supply, so a diagnosis of hypothyroidism suggests the rest of the body has even less iodine than the thyroid gland. Other side effects of hypothyroidism include depression, extreme tiredness, feeling cold, a tendency towards gaining weight and for constipation – everything slows down in the body when there is inadequate thyroid hormone or when it is present but not functioning correctly.
     It is more comfortable to not weigh an excessive amount and it is more comfortable to have energy and not feel depressed and cold.
     Showing the two pictures below is again, not about “body-shaming,” but was to give some idea of my past. Overweight women are somewhat invisible to men and to other women who care a lot about image. I have the social skills of an overweight woman, not those of a woman used to fending off unwanted attention from strangers or old acquaintances. I’ve never been to a fancy “cocktail party” if such a thing still occurs outside an episode of Mad Men (aka/the 1950’s). Or – more accurately – I have the social skills of someone with child trauma issues who may not have tried much in life and never gained experience and learned better skills.
     It takes a while to learn what you don’t know and further, to learn how many layers of not-knowing-what-you-didn’t-know and that you’ll have to learn about and work through before you will really get to the core issue or issues.
     A core issue revealed in the first picture is hyperthyroidism – I look thinner than typical for me. In the second picture I’m heavier but that was the weight that stubbornly stuck no matter how hard I tried to diet and exercise it off – until I took the large dose iodine supplement. My problem turned out to be the selenium. I didn’t learn about that until later after having developed hyperthyroid symptoms. Autoimmune thyroid problems can fluctuate between hypothyroid – low activity, and hyperthyroid – elevated activity. The first picture is me with hyperthyroidism and the second picture is hypothyroid.
     We all do need iodine though. I have to limit how much I eat now because I still have an overactive autoimmune thyroid condition. I do eat some iodine foods but not much iodized products or any supplements and I do try to eat selenium rich foods regularly, which is about two Brazil nuts per day.
     There aren’t many foods naturally rich in selenium. Coastal ocean microbes transform it from the form found in the ocean water into a form that can be carried in water droplets in the atmosphere where it is rained onto Brazil nut trees in the Amazon rain forest – isn’t our planet amazing?
We all need iodine.
This is how I spent most of my years as an adult, before I took iodine supplements.

The rate of infants born with congenital hypothyroidism has been escalating, baffling many, unless you consider an older diagnostic term – cretinism or iodine deficiency. Cretinism is somewhat reversible if the infant receives adequate iodine after diagnosis, the thyroid gland would grow and begin to produce hormone naturally. If the infant is treated only with synthetic thyroid hormone, then organ development would continue to suffer and the baby will probably need the drug for the rest of its life. Weight gain, fatigue, apathy and depression are common symptoms in adults and children born hypothyroid typically are petite and can have reduced IQ. Women can’t grow babies out of synthetic hormone, but that is what they usually are given if diagnosed with hypothyroidism instead of iodine deficiency.

All of our glands need iodine not just the thyroid gland. The pineal gland, also known in more  ancient terms as our Inner Eye, [crystalinks], has the second largest uptake of iodine and it is crucial for melatonin and a good night’s sleep. [5, 6] The mammary and prostate glands need iodine as well. Prostate and breast cancer also may involve an underlying iodine deficiency [2, 3] and the substitution of bromide, perchlorate and/or fluoride.

Lab tests have become a primary diagnostic tool and if the science underlying their use was wrong then the diagnosis based on the tests may not be very reliable. Our bodies have learned how to fool the lab test’s expectations of goiter by producing thyroid hormone containing fluoride or bromide. The gland is functioning normally but the hormone it is producing won’t prevent the symptoms and malfunction of hypothyroidism.

I had all those symptoms, but my lab tests were normal and therefore I was normal, or so I was told. However, after attending a seminar by Dr. Brownstein, I started a high dose iodine supplement that is equivalent to the amount of iodine provided by the sea weed in the traditional Japanese diet. The supplement that I have taken daily for six years contains 83 times more iodine than our current RDA. Our national guideline for iodine has not been changed since it was created in the 1940’s. Salt doesn’t have that much added to it and we aren’t really using much iodized table salt anymore. Do we reach for the salt shaker when we think about any other vitamin

It is important to get adequate amounts of the trace mineral selenium when supplementing with iodine, especially when using a large dose of iodine. Selenium is essential for the enzyme that breaks down excessive amounts of the active thyroid hormone. Excessive thyroid hormone can cause hyperthyroidism which can be associated with extreme mood and physical symptoms. Selenium can be toxic when excessive amounts are consumed for months.

Approximately two Brazil nuts provide the recommended daily goal of 200 micrograms of selenium. A one-a-day or prenatal vitamin would likely include 200 mcg of selenium. “Selenium” [ods.od.nih.gov/factsheets/selenium/]

A peer reviewed article with seaweed nutrient content information suggests that there is a wide range in iodine levels between different types of seaweed and between different samples of the same type of seaweed. [10]

The case study does not mention selenium. Hyperthyroid problems induced by abrupt increased intake of iodine may be mitigated by increasing selenium intake at the same time.

Kelp supplements can contain an unreliable amount of iodine. Out of 17 supplements tested the iodine content ranged from 45 micrograms to 57,000 micrograms. [1]

The kelp supplements content as tested is unreliable and potentially dangerous due to the unknown amount that might be contained. Seaweed also may contains goiterogens that interfere with thyroid function and occasionally toxins or other contaminants can be present due to the variability in ocean waters. [healthlibrary.epnet.com/GetContent.aspx?token=af362d97-4f80-4453-a175-02cc6220a387&chunkiid=21786 ]

Excessive iodine chronically can lead to toxicity side effects that include acne, a metallic taste in the mouth, a persistent mild cough and nasal discharge. The metallic taste can be a short term side effect due to bromide stores being exchanged for iodine. The RDA has been 150 micrograms. The Iodoral supplement that I have been using for six years contains 1250 micrograms of iodine/iodide which is a mega dose but is consistent and known, breaking the tablets and using a portion for a smaller daily dose is possible.

Those at increased risk of developing hypothyroidism include: Postpartum women, Women with family history of autoimmune thyroid disorders (AITD), Those with previous head, neck, or thyroid surgery or irradiation, Those with other autoimmune endocrine disorders (e.g., type 1 diabetes mellitus, adrenal insufficiency, or ovarian failure), Those with nonendocrine autoimmune disorders (e.g., vitiligo, multiple sclerosis), Patients with primary pulmonary hypertension, Those with Down’s or Turner’s syndromes. 

The following biological activities are particularly impaired by hypothyroidism: Calorigenic modification, Oxygen consumption throughout most tissues, Protein, fat, and carbohydrate metabolism, Augmentation of calcium ATPase activity in cardiac muscle, Mitochondrial ATP production, G-protein-coupled membrane receptor activity, Organ-specific effects. 

The clinical manifestations of hypothyroidism (see Symptoms) are the result of effects occurring at the molecular level because of the impact of thyroid hormone insufficiency.” Read more: [medicinalplants.us/hypothyroidism ]

December 15, 2011 addition:

  • “Asian countries, such as Japan, have low rates of breast cancer, while Western countries have cancer rates that are many times higher. 25,26 However, when Japanese girls are raised on westernized diets, their rate of breast cancer increases dramatically.”  [cancerproject.org/survival/cancer_facts/breast.php]
  • Some statistics about prostate and breast cancer rates compared to iodine levels. [drdavidbrownstein.blogspot.com/2009/05/rapid-increase-in-thyroid-cancer.html]
  • www.faostat.fao.org – world food supply statistics. ***The world three year average consumption of Aquatic Plants ( aka seaweed) for 2007-2005 is zero if you remove the three out-lying values out of the 154 countries with data. The countries with Aquatic Plant consumption are China – 20.39 grams/capita/day, Japan- 4.02 gr/cap/day, and the Republic of Korea – 35.28 gr/capita/day. [faostat.fao.org/site/610/DesktopDefault.aspx?PageID=610#ancor]
  • The Japanese intake of 4.02 grams Aquatic Plants may provide a safe amount of iodine without an excess of goiterogens that may be provided in the Chinese 20.39 average intake or the Republic of Korea’s 35.28 grams/capita/day of Aquatic Plants.
  • The World’s Healthiest Foods website,”Sea Vegetables, What’s New and Beneficial about Sea Vegetables?” – recipes and health information for a variety of sea vegetables. [whfoods.com/genpage.php?tname=foodspice&dbid=135 ]
  • Nutrient information for Kelp lists iodine content as 415 micrograms per 20 gram serving. The U.S. Nutrient Data Base # 11445, Seaweed, Kelp Raw did not have a line for Iodine content. Based on the wide range in content found by the research team in citation #1 it would be hard to estimate how much iodine the Japanese, Chinese, and Republic of Korea citizens might be consuming on average – but it is clearly an excellent source. [whfoods.com/genpage.php?tname=nutrientprofile&dbid=51]

For more on hypothyroidism and pickle’s value as a side dish, see my post:  [Vitiligo, hypothyroidism and melanin]

Plastics, pesticides, herbicides and other chemicals may be a major cause of the feminizing of our young men [13] but the lack of iodine is also at fault. The prostate and testicles need iodine in addition to the thyroid, mammary and pineal glands. Switch to stainless steel drinking bottles and filtered water if you are worried about chemicals that disrupt the endocrine system; avoid soda (metal cans are lined with plastic) it is so acidic that it is leaching magnesium from you anyway; and take a high dose iodine or tested seaweed supplement. Boys will only continue to be boys if we provide their pregnant mothers and their growing bodies with nutritious building blocks. We still can’t build a functioning body out of pharmaceuticals or synthetic hormones.

/Disclosure: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./
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  1. Norman JA, Pickford CJ, Sanders TW, et al. Human intake of arsenic and iodine from seaweed-based food supplements and health foods available in the UK. Food Addit Contam. 1988;5:103-109. www.drbrownstein.com/homePage.php
    [drdavidbrownstein.blogspot.com/2009/05/rapid-increase-in-thyroid-cancer.html]
  2. Most Asian Men Have Better Prostate Cancer Survival Rates, Finding could help to govern treatment approaches, study suggests. By Steven Reinberg, HealthDay Reporter,  [abcnews.go.com/Health/Healthday/story?id=4508275&page=1]
  3. Race Plays A Key Role In Prostate Cancer Survival Rates, sciencedaily.com,  [sciencedaily.com/releases/2006/06/060613072943.htm]
  4. Watanabe R, Hanmori K, Kadoya H, Nishimuta M, Miyazaki H, Nutritional Intakes in community-swelling older Japanese adults: high intakes of energy and protein based on high consumption of fish, vegetable and fruits provide sufficient micronutrients, J Nutri Sci Vitaminol (Tokyo). 204 Jun: 50(3): 184-95, [ncbi.nlm.nih.gov/pubmed/15386931]
  5. On Pineal calcification and its relation to subjective sleep perception: a hypothesis-driven pilot study, Volume 82, Issue 3, Pages 187-191 (30 June 1998)  [psyn-journal.com/article/S0925-4927%2898%2900013-4/abstract]
  6. Richard Mahlberg, Thorsten Kienast, Degree of pineal calcification (DOC) is associated with polysomnographic sleep measures in primary insomnia patients, [sleep-journal.com/article/S1389-9457%2808%2900154-8/abstract
  7.  “Selenium” [ods.od.nih.gov/factsheets/selenium/]
  8. [ncbi.nlm.nih.gov/pmc/articles/PMC1924637/table/tbl3/]
  9. [ncbi.nlm.nih.gov/pmc/articles/PMC1924637/]
  10. Müssig, K., Thamer, C., Bares, R., Lipp, HP., Häring, HU., Gallwitz, B., Iodine-Induced Thyrotoxicosis After Ingestion of Kelp-Containing Tea, J Gen Intern Med. 2006 June; 21(6): C11–C14. doi: 10.1111/j.1525-1497.2006.00416.x. PMCID: PMC1924637
  11. Leung, A.M., Pearce, E.N., Braverman, L.E., Iodine Content of Prenatal Multivitamins in the United States, N Engl J Med 2009; 360:939-940, [nejm.org/doi/full/10.1056/NEJMc0807851]
  12. Jian-Ying Zhan, Yu-Feng Qin and Zheng-Yan Zhao, Neonatal screening for congenital hypothyroidism and phenylketonuria in China, World Journal of Pediatrics Vol. 5, Number 2, 136-139,  [springerlink.com/content/w7054w4550233404/]
  13. Why so many teen-age boys are wimpy, irresponsible, unmotivated and bored: one of the reasons, gatesofhorn.com,  [gatesofhorn.com/blog/why_so_many_teen_age_boys_are_wimpy_irresponsible_unmotivated_and_bored_one_of_the_reasons]

I need to talk about iodine a bit before I get to the vitamin D and calcium story. I don’t think I would have kicked my migraine and autoimmune problems if I hadn’t conquered my undiagnosed hypothyroidism first. The body can’t do anything without energy and the thyroid hormone is our energizer. Hypothyroid bodies become super efficient at not wasting energy and people can gain weight on 600 calories a day – you can’t live on that. Extreme fatigue, depression, apathy, hair loss, infertility and miscarriages are also common symptoms.