original Prilosec warning edited

A recently released government statement states that some people using proton pump inhibitors for more than a year may end up with low magnesium levels. [1] Low magnesium can be life threatening but it can also just be tiring and painful. Magnesium helps block over active muscle cramping and reduces headaches and diabetic nerve pain. It is essential for white blood cell function and prevention of osteoporosis.

The proton pump inhibitor medications may be inhibiting the active absorption of magnesium in the intestines in some individuals. In other words, the drug may be blocking proton pumps in the intestinal cell membrane that are necessary to actively move magnesium from the intestines into the cell. Some people were not able to improve their magnesium levels  with supplements until after the medication was stopped. Magnesium levels dropped again when the medication was re-started.

A simple serum magnesium test only shows acute deficiency. If you are concerned about your risk of chronic magnesium deficiency then ask for a red blood cell or muscle cell biopsy lab test to check intracellular serum levels.  The serum lab test that is commonly used usually doesn’t show a chronic magnesium deficiency. Only one percent of the body’s magnesium is found in the blood serum. The concentration is carefully regulated and deficiency would be severe or acute before serum levels of magnesium would drop.
Basing a decision on observable symptoms may be more helpful and budget friendly. Skip the blood tests or look at calcium level in the CBC panel. Hypocalcemia is a protective measure the body will adopt if possible when magnesium is low. Potassium levels can also be low. [3]

If you are having symptoms then a magnesium foot soak or bath in Epsom salts can bypass the intestinal absorption problems and provide some relief- while you are working on stopping the medication with your medical provider. Magnesium containing skin creams like the Ahava line may also provide relief. (I still like the body lotion but had to stop the face product – sensitivity reaction).

I have recently started using a Magnesium Glycinate supplement that I found at my local Food Coop . The tablet is quite large and sweet because it is a glyco-compound  which should help it dissolve and absorb better.  (See my blogs about the glycocalyx for more information about benefits of glyco-nutrients.) However it is more expensive than my mixed magnesium caplet, which contains magnesium oxide, citrate and malate. The only negative side effect that may occur with magnesium supplements is temporary loose stools (not explosive diarrhea, unless it was a really big dose like Milk of Magnesia, just really soft BM). The glycinate form may not trigger the smooth muscle fiber relaxation the way the free ions would. It is the rapid relaxation of the intestinal muscle lining that can trigger diarrhea/loose stools, so the magnesium glycinate may cost a bit more ($17 vs $6)  but if it is better absorbed and is less likely to cause side effects than it seems like a fair deal.

Click here to read more about magnesium and how six dollars a month could restore more function while reducing symptoms (aka side effects of dysfunction) 

A Government Statement you may not hear about [1, 2]:
Proton Pump Inhibitor drugs (PPIs): Drug Safety Communication – Low Magnesium Levels Can Be Associated With Long-Term Use
Prescription PPIs include Nexium (esomeprazole magnesium), Dexilant (dexlansoprazole), Prilosec (omeprazole), Zegerid (omeprazole and sodium bicarbonate), Prevacid (lansoprazole), Protonix (pantoprazole sodium), AcipHex (rabeprazole sodium), and Vimovo (a prescription combination drug product that contains a PPI (esomeprazole magnesium and naproxen).
Over-the-counter (OTC) PPIs include Prilosec OTC (omeprazole), Zegerid OTC (omeprazole and sodium bicarbonate), and Prevacid 24HR (lansoprazole).
[Posted 03/02/2011]
AUDIENCE: Consumer, Gastroenterology, Family Practice
ISSUE: FDA notified healthcare professionals and the public that prescription proton pump inhibitor (PPI) drugs may cause low serum magnesium levels (hypomagnesemia) if taken for prolonged periods of time (in most cases, longer than one year). Low serum magnesium levels can result in serious adverse events including muscle spasm (tetany), irregular heartbeat (arrhythmias), and convulsions (seizures); however, patients do not always have these symptoms. Treatment of hypomagnesemia generally requires magnesium supplements. In approximately one-quarter of the cases reviewed, magnesium supplementation alone did not improve low serum magnesium levels and the PPI had to be discontinued.
BACKGROUND: PPIs work by reducing the amount of acid in the stomach and are used to treat conditions such as gastroesophageal reflux disease (GERD), stomach and small intestine ulcers, and inflammation of the esophagus.
RECOMMENDATION: Healthcare professionals should consider obtaining serum magnesium levels prior to initiation of prescription PPI treatment in patients expected to be on these drugs for long periods of time, as well as patients who take PPIs with medications such as digoxin, diuretics or drugs that may cause hypomagnesemia. For patients taking digoxin, a heart medicine, this is especially important because low magnesium can increase the likelihood of serious side effects. Healthcare professionals should consider obtaining magnesium levels periodically in these patients. For additional information, refer to the Data Summary section of the FDA Drug Safety Communication.
Healthcare professionals and patients are encouraged to report adverse events, side effects, or product quality problems related to the use of these products to the FDA’s MedWatch Safety Information and Adverse Event Reporting Program:
  • Complete and submit the report Online: www.fda.gov/MedWatch/report.htm1
  • Download form2 or call 1-800-332-1088 to request a reporting form, then complete and return to the address on the pre-addressed form, or submit by fax to 1-800-FDA-0178

2. http://www.medscape.com/viewarticle/738442, PPI-Related Hypomagnesemia: Putting it in Perspective, David A. Johnson, MD, Posted: 03/07/2011, From: Medscape Gastroenterology > Johnson on Gastroenterology

3.    http://jasn.asnjournals.org/content/20/11/2291.long  Kevin J. Martin,  Esther A. González and Eduardo Slatopolsky, Clinical Consequences and Management of Hypomagnesemia,  doi: 10.1681/ASN.2007111194 (JASN November 1, 2009 vol. 20 no. 11 2291-2295)

Stomach and duodenal ulcer diet, herbs, vitamins, natural treatment with diet, supplements and home remedy by Ray Sahelian, M.D.
“Melatonin or l-tryptophan accelerates healing of gastroduodenal ulcers in patients treated with omeprazole. Three groups (A, B and C) of 14 patients in each treatment group with gastroduodenal chronic ulcers were treated with omeprazole (20 mg twice daily) combined either with placebo (group A), melatonin (group B) or with Trp (group C). On day 7, omeprazole by itself (group A) had not healed any ulcers, but four ulcers were healed with omeprazole plus melatonin and two with omeprazole plus tryptophan. At day 21, all ulcers were healed in patients treated with melatonin or Trp, but only 10-12 ulcers were healed in placebo-treated patients. Plasma gastrin level also rose significantly during treatment with omeprazole plus melatonin or Trp, but it was also significantly increased in patients treated with omeprazole plus placebo. Plasma ghrelin levels did not change significantly after treatment with melatonin or Trp, while plasma leptin increased significantly in patients treated with melatonin or Trp but not with placebo. We conclude that melatonin or Trp, when added to omeprazole treatment, accelerates ulcer healing and this likely depends mainly upon the significant increments in plasma melatonin. J Pineal Res. 2011.”
“Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.).
Ataturk University, Erzurum, Turkey.
J Ethnopharmacol. 2004.
In this study, water extract of stinging nettle (Urtica dioica L.) was studied for antioxidant, antimicrobial, antiulcer and analgesic properties. The antioxidant properties of stinging nettle were evaluated using different antioxidant tests, including reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities. Stinging nettle had powerful antioxidant activity. The 50, 100 and 250 microg amounts of stinging nettle showed 39, 66 and 98% inhibition on peroxidation of linoleic acid emulsion, respectively, while 60 microg/ml of alpha-tocopherol, exhibited only 30% inhibition. Moreover, stinging nettle had effective reducing power, free radical scavenging, superoxide anion radical scavenging, hydrogen peroxide scavenging, and metal chelating activities at the same concentrations. In addition, total phenolic compounds in the stinging nettle were determined as pyrocatechol equivalent. Stinging nettle also showed antimicrobial activity against nine microorganisms, antiulcer activity against ethanol-induced ulcerogenesis and analgesic effect on acetic acid-induced stretching.”5. http://www.raysahelian.com/methylmethioninesulfonium.html
***cysteine and MMSC (methylmethionine sulfonium chloride) supplementation for ulcers6. http://www.gihealth.com/newsletter/previous/071.html

***This 2007 newsletters is assuring us of the safety of the PPI’s for the heart (but turns out not for everybody’s heart – the genetic canaries who handle magnesium and calcium a little differently do need to avoid PPI use.  The increased fracture risk reported would be related not just to decreased calcium absorption but also to the decreased magnesium absorption in the genetically more at risk individuals.

“There was one study reported from England last year that suggested that acid suppression from PPI treatment may reduce calcium absorption from the diet and increase the risk of hip fracture, especially in the elderly. The study found a similar but smaller risk of hip fractures for another class of acid-fighting drugs called H2 blockers. Those drugs include Tagamet, Zantac, Axid and Pepcid. So far, this conclusion seems true, but most doctors feel that this risk can be averted by properly monitoring the bone density of elderly people taking the drugs and recommending calcium-rich diets to all patients.”

 Vladimir Chubanov *Siegfried Waldegger , Michael Mederos y Schnitzler *Helga Vitzthum , Martin C. Sassen Hannsjörg W. Seyberth , Martin Konrad , and  Thomas GudermannDisruption of TRPM6/TRPM7 complex formation by a mutation in the TRPM6 gene causes hypomagnesemia with secondary hypocalcemia doi: 10.1073/pnas.0305252101 PNAS March 2, 2004 vol. 101 no. 9 2894-2899§ To whom correspondence should be addressed at: Institute for Pharmacology and Toxicology, Philipps University Marburg, Karl-von-Frisch Strasse 1, 35033 Marburg, Germany. E-mail: guderman@staff.uni-marburg.de.
Magnesium references From Bibliography for Dietitian Recommends Stop Vitamin D and Calcium ASAP 


8. http://www.ijkd.org/index.php/ijkd/article/view/140 Assadi, F., Hypomagnesemia, An Evidence-Based Approach to Clinical Cases, (Iranian Journal of Kidney Diseases, Vol 4, No 1 (2010)
18. http://www.ncbi.nlm.nih.gov/pubmed/20081245 Magdalena Bujalska, Helena Makulska-Nowak, Stanis³aw W. Gumuka Magnesium ions and opioid agonistsin vincristine-induced neuropathy , Department of Pharmacodynamics, Medical University of Warsaw, Krakowskie Przedmieoecie 26/28, PL 00-927 Warszawa, Poland
19. Magnesium: an emerging drug in anaesthesia, , Editorial I, M. F. M. James, British Journal of Anaesthesia, 103 (4): 465-7 (2009) DOI:10.1093/bja/aep242
23. http://www.ncbi.nlm.nih.gov/pubmed/17823441 Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W., The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. ( Am J Clin Nutr. 2007 Sep;86(3):743-51)
24. Joan L Caddell, Geriatric cachexia: a role for magnesium deficiency as well as for cytokines?, Letter to the Editor, , (Am J Clin Nutr 2000;;71:844-53. pp 851-853)
25. Carl J Johnson, M.D., Donald R. Peterson, M.D., Elizabeth K. Smith, PhD, Myocardial tissue concentrations of magnesium and potassium in men dying suddenly from ischemic heart disease, (Am J Clin Nutr 32: MAY 1979, pp 967-970)
29. Geeta Sharma and Charles f Stevens, A mutation that alters magnesium block of N-methyl-D-aspartate receptor channels, Pub: Proceedings of the National Academy of Sciences of The united States 93.n17 (August 20, 1996): pp9259+. InfoTrac General Science Collection.
30. Beasley R, Aldington S, Magnesium in the treatment of asthma..Medical Research Institute of New Zealand, Wellington, New Zealand., Richard.Beasley@mrinz.ac.nz, Curr Opin Allergy Clin Immunol. 2007 Feb;7(1):107-10
32. Maged M. Costantine, MD, Steven J. Weiner, MS, Effects of Antenatal exposure to Magnesium Sulfate on Neuroprotection and Mortality in Preterm Infants: A Meta Analysis, Obstet Gynecol. 2009 August; 114(2 Pt 1): 354-364 DOI:10.1097/AOG0b013e3181ae98c2
33. Burton M. Altura, Bella T. Altura and Anthony Carella., Magnesium deficiency-induced spasms of umbilical vessels: relation to preeclampsia, hypertension, growth retardation. Pub:Science, 221 (July 22, 1983): pp376(2)
34. Burton M. Altura, Bella T. Altura, Asefa Gebrewold, Harmut Ising and Theo Gunther, Magnesium deficiency and hypertension: correlation between magnesium-deficient diets and microcirculatory changes in situ.,. Pub: Science, 223.(March 23, 1984): pp1315(3).
37. http://ahavaus.com/site/dead_sea_wonders.html Line of skin care products containing magnesium.
42. Magnesium intake from food and supplements is associated with bone mineral density in healthy older white subjects. (elderly health), Kathryn M. Ryder, Ronald I Shorr, Andrew J. Bush, Tamara Harris, Katie Stone and Frances A Tylavsky. Journal of the American Geriatrics Society, 53.11 (Nove 2005): p1875-1881. Academic One File. Web. 13 Dec. 2010
43. DASH Diet May Cut Heart Disease Risk, – source John Hopkins Medicine, Today’s Dietitian, Vol . 12, No. 10, Oct. 2010, p 25
44. Christine Feillet-Coudray, Charles Coudray, Zjean-Claude Tressol, Denise Pepin, Andrzej Mazur, Steven A Abrams, Exchangeable magnesium pool masses in healthy women: effects of magnesium supplementation, Yves Rayssiguier, Am J Clin Nutr 2002;75;72-8
45. http://www.highbeam.com/doc/1P3-2180507851.htmlResearchers Identify Protein that Regulates Magnesium and Can Restart Stem Cells.” Targeted News Service. Targeted News Service LLC. 2010. HighBeam Research. 16 Feb. 2011 . “An international team led by researchers at the University of Medicine and Dentistry of New Jersey-Robert Wood Johnson Medical School has published new findings that demonstrate how a specific protein controls the body’s ability to balance magnesium levels. Magnesium is an essential element for good health and is critical to more than 300 biochemical reactions that occur in the body. “Currently more than half of the US population does not consume an adequate amount of magnesium in their diet,” said Alexey G. Ryazanov, Ph.D., one of the study’s authors and a professor of pharmacology and member of The Cancer Institute of New Jersey at UMDNJ-Robert Wood Johnson Medical School. “Magnesium deficiency may be associated with many medical disorders including hypertension, atherosclerosis, anxiety, asthma and a host of other disorders.” “The team of researchers from the United States, France and Poland demonstrated for the first time that a protein called TRPM7 plays a key role in the maintenance of magnesium homeostasis (balance within the body) and is essential for proliferation of embryonic stem cells.”
77. Neuromed Phamaceuticals and Merck & Co., Inc. Announce Agreement for Novel N-type Calcium channel Compounds, from Business Wire, March 20, 2006, High Beam Research – **Neuromed is a pharmaceutical company focusing on calcium channel blockers. “blocking pain signaling through the N-type calcium channel is a novel approach for the treatment of pain” said Christopher Gallen,MD, PhD, President and Chief Executive Officer of Neuromed. **Providing adequate magnesium would be a less novel way to block nerve pain caused by overexcitation by excess calcium. Citation #9 demonstrated that diabetic neuropathy pain could be reduced by magnesium injection alone – why bother with the opioid or the synthetic calcium channel blocker. They are an expensive and dangerous class of pharmaceuticals that would be pretty much not necessary if we weren’t being drained of magnesium reserves by excessive calcium and acidity intakes.
95 [also 3 above].      http://jasn.asnjournals.org/content/20/11/2291.long  Kevin J. Martin,  Esther A. González and Eduardo Slatopolsky, Clinical Consequences and Management of Hypomagnesemia,  doi: 10.1681/ASN.2007111194 (JASN November 1, 2009 vol. 20 no. 11 2291-2295)
96.      http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2639130/?tool=pubmed  Karl T. Weber, William B. Weglicki, and Robert U. Simpson, Macro- and micronutrient dyshomeostasis in the adverse structural remodelling of myocardium,  (Cardiovasc Res. 2009 February 15; 81(3): 500–508.) Published online 2008 October 3. doi: 10.1093/cvr/cvn261.
More Magnesium references:
  1. “Possible Interactions with: Magnesium,” http://www.umm.edu/altmed/articles/magnesium- 000968.htm.
  2. B Grimaldi, “The central role of magnesium deficiency in Tourette’s syndrome: causal relationships between magnesium deficiency, altered biochemical pathways and symptoms relating to Tourette’s syndrome and several reported comorbid conditions,” Medical Hypotheses 58, no. 1 (1, 2002): 47-60.
  3. G Eby, “Rescue treatment and prevention of asthma using magnesium throat lozenges: Hypothesis for a mouth–lung biologically closed electric circuit☆,” Medical Hypotheses 67, no. 5 (2006): 1136-1141.
  4. “Nut consumption and risk of coronary heart disease… [Curr Atheroscler Rep. 1999] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/11122711.
  5. “Magnesium deficiency and metabolic syndrome: stres… [Magnes Res. 2010] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/20513641.
  6. “Magnesium and the inflammatory response: potential… [Arch Biochem Biophys. 2007] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/16712775.
  7. “[Magnesium and inflammation: lessons from animal m… [Clin Calcium. 2005] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/15692164.
  8. P Chambers, “Lone atrial fibrillation: Pathologic or not?,” Medical Hypotheses 68, no. 2 (2007): 281-287.
  9. “Complementary vascular-protective actions of magnesium and taurine: A rationale for magnesium taurate,” http://www.medical-hypotheses.com/article/S0306-9877(96)90007-9/abstract.
  10. Abe E. Sahmoun and Brij B. Singh, “Does a higher ratio of serum calcium to magnesium increase the risk for postmenopausal breast cancer?,” Medical Hypotheses 75, no. 3 (9, 2010): 315-318.
  11.  “Epidemiological evidence associating dietary calci… [Am J Nephrol. 1986] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/2950755.
  12. “High fructose consumption combined with low dietar… [Magnes Res. 2006] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/17402291.
  13. ..AppDataRoamingMozillaFirefoxProfiles5z5xh8vb.defaultzoterostorage4MGSRXSW9789241563550_eng.pdf   Cotruvo J, Bartram J, eds. Calcium and Magnesium in Drinking-water : Public health significance, Geneva, World Health Organization, 2009.
  14. “Protein peroxidation, magnesium deficiency and fib… [Magnes Res. 1996] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/9247880.
  15. E Planells et al., “Effect of magnesium deficiency on vitamin B2 and B6 status in the rat,” Journal of the American College of Nutrition 16, no. 4 (August 1997): 352-356.
  16. Sivan Ben-Avraham et al., “Dietary strategies for patients with type 2 diabetes in the era of multi-approaches; review and results from the Dietary Intervention Randomized Controlled Trial (DIRECT),” Diabetes Research and Clinical Practice 86 Suppl 1 (December 2009): S41-48.
  17. “Utility of magnesium as antiarrhythmic agent reviewed. – Health & Medicine Week | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-121345520.html.
  18. Barbara Chipperfield and JohnR. Chipperfield, “Relation of Myocardial Metal Concentrations to Water Hardness and Death-Rates from Ishchaemic Heart Disease,” The Lancet 314, no. 8145 (October 6, 1979): 709-712.
  19. Barbara Chipperfield et al., “Magnesium and Potassium Content of Normal He3art Muscle in Areas of Hard and Soft Water,” The Lancet 307, no. 7951 (January 17, 1976): 121-122.
  20. “Regulation of Contraction in Striated Muscle — Gordon et al. 80 (2): 853 — Physiological Reviews,” http://physrev.physiology.org/cgi/content/full/80/2/853.
  21. “Potassium, calcium, magnesium, and sodium levels i… [Clin Lab. 2010] – PubMed result,” http://www.ncbi.nlm.nih.gov/pubmed/21086788.
  22. “Magnesium: Its proven and potential clinical significance.(Statistical Data Included) – Southern Medical Journal | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-82553295.html#.
  23. “Magnesium Treatment for Sudden Hearing Loss – The Annals of Otology, Rhinology & Laryngology | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-679636211.html#.
  24. “Magnesium supplementation decreases oxidative stress in diabetic rats. – Biotech Week | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-104471960.html#.
  25. “Magnesium requirement of kittens is increased by high dietary calcium – The Journal of Nutrition | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-37651279.html#.
  26. Daniel G. Chausow et al., “Experimentally-induced magnesium deficiency in growing kittens,” Nutrition Research 6, no. 4 (April 1986): 459-468.
  27. Yuhei Kawano et al., “Effects of Magnesium Supplementation in Hypertensive Patients : Assessment by Office, Home, and Ambulatory Blood Pressures,” Hypertension 32, no. 2 (August 1, 1998): 260-265.
  28. Robert E. Kleiger et al., “Effects of chronic depletion of potassium and magnesium upon the action of acetylstrophanthidin on the heart,” The American Journal of Cardiology 17, no. 4 (April 1966): 520-527.
  29. Andrew D Hershey, “Current approaches to the diagnosis and management of paediatric migraine,” The Lancet Neurology 9, no. 2 (2, 2010): 190-204.
  30. A M Gordon and E B Ridgway, “Cross-bridges affect both TnC structure and calcium affinity in muscle fibers,” Advances in Experimental Medicine and Biology 332 (1993): 183-192; discussion 192-194.
  31. Karin Ladefoged and Kikki Hagen, “Correlation between concentrations of magnesium, zinc, and potassium in plasma, erythrocytes and muscles,” Clinica Chimica Acta 177, no. 2 (October 14, 1988): 157-166.
  32. “Common genetic variants of the ion channel transient receptor potential membrane melastatin 6 and 7 ( TRPM6 and TRPM7 ), magnesium intake, and risk of type 2 diabetes in women.(Research article)(Report) – BMC Medical Genetics | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-193482837.html#.
  33. M Fu et al., “Association between Unhealthful Eating Patterns and Unfavorable Overall School Performance in Children,” Journal of the American Dietetic Association 107, no. 11 (11, 2007): 1935-1943.
  34. “Antenatal magnesium treatment and neonatal illness severity as measured by the Score for Neonatal Acute Physiology (SNAP) – Journal of Maternal – Fetal & Neonatal Medicine | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-856244151.html#.
  35. “Acid-Base Status Affects Renal Magnesium Losses in Healthy, Elderly Persons1 – The Journal of Nutrition | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-1123831511.html#.
  36. “Ancient Minerals Launches Comprehensive Online Magnesium Health Resource. – PRWeb Newswire | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-241203537.html#.
  37. K Michaelsen, “Inadequate Supplies of Potassium and Magnesium in Relief Food? Implications and Countermeasures,” The Lancet 329, no. 8547 (6, 1987): 1421-1423.
  38. “High Dietary Intake of Magnesium May Decrease Risk of Colorectal Cancer in Japanese Men1,2 – The Journal of Nutrition | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-1998563311.html.
  39. “Magnesium – The Clinical Advisor : For Nurse Practitioners | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1P3-2195246591.html.
  40. “Magnesium prevents chemotherapy side effects.(Editorial)(Report) – Townsend Letter | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-206620332.html#.
  41. J Caddell, “Magnesium Deprivation in Sudden Unexpected Infant Death,” The Lancet 300, no. 7771 (8, 1972): 258-262.
  42. “Magnesium builds bones in pre-pubertal and adolescent girls.(ABSTRACTS OF INTEREST)(Clinical report) – Original Internist | HighBeam Research – FREE trial,” http://www.highbeam.com/doc/1G1-166995340.html#.
  43. J D Potter, S P Robertson, and J D Johnson, “Magnesium and the regulation of muscle contraction,” Federation Proceedings 40, no. 12 (October 1981): 2653-2656.

Pancakes in a jiffy Quick Bread Mix

Pancake mix can be made at home for less money and less packaging. The mix can be easily adapted to make other favorite quick breads like muffins and biscuits. Cornbread can be made if cornmeal is added.Jiffy Mixes are actually a line of Michigan baking products made in Chelsea, Michigan. http://www.jiffymix.com/ (I love Jiffy Mixes but I cheat and make my own!)

This mix is not gluten free. It is based on a half and half mixture of white flour for more gluten content, to support a light airy baked good, combined with whole wheat flour and wheat germ to boost the natural nutrients found in the whole wheat berry.

My basic Quick Bread Mixcontains dry milk powder so that only water, oil, egg and sweetener will need to be added when making a speedy batch of pancakes, muffins or biscuits.

Basic Quick Bread Mix
(makes about 15 cups of dry Quick Bread Mix)

5 cups White Flour  (or any mixture of 10-12 cups flour)
5 cups Whole Wheat Flour
2 cups Wheat Germ (or 2 cups flour or very finely crushed dry cereal flakes)
4 Tablespoons Baking Powder
2 Tablespoons Salt
3 cups Dry Powdered Milk (optional – if liquid milk or milk substitute is to be used instead of water for baking.)

makes about 8-12 three inch diameter pancakes.

1 1/2 cups Quick Bread Mix
1 egg

Pancake batter is drippy but not watery.

1 Tablespoon Sugar (helps brown the surface)
1 Tablespoon Oil
1 cup water plus extra 1/8 cup water as needed – if batch is thick or if thinner pancakes are desired.

Pancake batter is fairly runny but will mound slightly and the back of the spoon may be used to spread out the pancake batter to an even thickness. Fresh or thawed blueberries or chocolate chips can be dropped in the dough in each individual pancake or mixed in the batter. The sticky sweetness can burn to the pan more.

Pancakes take about 2-3 minutes per side on a medium hot skillet or large pan. Watch the surface for air bubbles to begin bubbling to the top and flip them for the first time after the bubbles have started to pop but haven’t all stopped rising to the surface. The second side can take just 1-2 minutes. The skillet may need to pulled from the heat if the pancakes are burning but are still raw in the middle.

A pastry blender, Amazon

makes about 9 three inch square biscuits
(bake for about 30 minutes at 375-400F)

3 cups Quick Bread Mix
1 stick margarine or butter
– using two knives, your hands or a pastry blender crumble the mix and butter together until granular – like floury rice crumbles instead of obvious bits of butter.

1 cup water – add and mix together.

Dump the dough onto a lightly floured work surface to fold the mass onto itself, squish down, fold again, squish down, repeat.

Add a little extra water by sprinkling on a spoonful or two if the crumbles aren’t sticking together well.

Powder the cutting board or table before the folding process or during as needed. If a little too much water was added just add a little more sprinkling of the Quick Bread Mix over the dough.

Eventually form the dough into a rectangle roughly 6 inches by 12 inches and about 1/1/2 inches thick  and then cut into 9 to 12 pieces. Perfect rounds was never the goal – crunch and taste but a more moist dense biscuit can be expected when using part whole wheat flour.

Basic Muffins

Makes one dozen. (about 25-30 minutes at 375 F)

2 1/2 cups Quick Bread Mix
1/2 to 3/4 cup Sugar
2 Eggs
1/2 cup Oil or 1 stick melted Butter or Margarine
1 teaspoon (tsp) Vanilla Extract *** and/or other flavor combinations and add ins
1 cup Water
or 1 cup Applesauce plus 1/8 cup water if needed
or 1/2 cup cooked pumpkin or cooked pureed sweet potato plus 1/2-3/4 cup water *

*Possible substitutions for the liquid. When milk powder is in the mix many other liquids can take the place. Orange juice or other fruit juice concentrates can be used in the concentrate form as a substitute for the liquid in the recipe and for part of the sweetener – depending on the family’s sweet tooth.  (Milk protein does add stability to the chemical mixture. Split pea soup powder that was made with no onion or other savory seasonings is a protein substitute worth trying in baking.)

  • Spiced Apple Muffin variation: 1 cup Applesauce instead of water. Flavoring: 1 teaspoon Vanilla plus 2 teaspoons Ginger powder, 1/2 tsp Cardamom powder and 1/2 tsp Nutmeg powder.
  • The Applesauce muffin flavor could be the simple vanilla – up to 1 Tablespoon of Vanilla could be used if that is the only flavor. 1/2 teaspoon to 1 teaspoon of cinnamon would be typical with applesauce.
  • Possible add-ins: 1/2 to 1 cup of raisins, currents or other chopped dried fruit – rehydrate for a few minutes with 1/4 cup very hot water; 1/2 to 1 cup chopped nuts; 1/2 to 1 cup finely grated carrot; a half package of chocolate chips; or a cup of blueberries fresh or thawed slightly; 1 cup finely diced raw apple or pear; – With additions the one dozen muffin cups get too full and a mini muffin pan can usually be filled in addition to the regular size muffin pan resulting in roughly 12 regular and 6-8 mini muffins / tart pan.

8 inch square pan – (bake for about 30 minutes at 375-400 F)

1 1/2 cups Quick Bread Mix
1 cup Cornmeal
1 teaspoon Baking Powder
1/4 to 1/2 cup Sugar
1/4 teaspoon Salt (a pinch)
1 stick Butter or Margarine – melted or Oil
2 Eggs
1 cup Water – add 1/8-1/4 cup extra if needed – let the pan stand for a few minutes out of the oven to allow moisture to hydrate the cornmeal and powdered milk granules. (the milk granules will remain visible.)

Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Quarks, bosons, and Abbess Zenkai Blanche Hartman

Believing more in the power of self healing and less in lab tests could buy more health. Working harder on defining life expectancy instead of death expectancy could lead to more quality of life or maybe just a little less worry along the way. More time to pick wildflowers could be an inexpensive bonus for anyone – they can be virtual flowers for allergy sufferers.  Any type of nature in symbols or actual plants have been found effective towards reducing stress and improving health.

How could a picture of flower heal? – Maybe it is calming energy – nature recognizing the beauty of organized nature, intimate to the connection of ourselves with our world.

Queen Anne’s Lace, solar art.

Excerpt from ”’A Beginner’s Mind”’ by Abbess Zenkai Blanche Hartman, [http://www.intrex.net/chzg/hartman4.htm]

‘In China, there was a teacher named Dizang (J.: Rakan) who had a student named Fayan (J.: Hogen). Dizang saw Fayan all dressed in his traveling clothes, with his straw sandals and his staff, and a pack on his back, and Dizang said, “Where are you going?” Fayan answered, “Around on pilgrimage.” Dizang said, “What is the purpose of pilgrimage?” Fayan said, “I don’t know.” Dizang said, “Not knowing is nearest.” Sometimes it’s translated as “Not knowing is most intimate.” Not knowing is nearest or most intimate.’

Not knowing is most intimate” – the most intimate or personally unique level may be the sub-atomic, quark-ian level.

Our protons and neutrons are made up of a balance of energy from three pairs of quarks. Their energy states change and the whole atom ‘s energy field is a result of the average of the three pairs of quarks. Our internal world may be a binary one with an on/off switch within every atom of our bodies – and our health.

A positive attitude versus a negative attitude can change the form that water freezes from a beautiful ornate crystalline lattice (snowflake) into a amorphous blob of ice. The work done on photography of water crystallizing into snowflakes by Dr Masuro Emoto shows us that a blessing or prayer before a meal might help align the fluid in the foods. Crystalline structure that is organized might promote better health. His work in water therapy has not been verified with replication but the idea that water crystals have to align to make an organized snowflake makes sense chemically. That is how a water droplet is formed, from alignment of the positive and negative areas of each individual molecule of water. Snowflake alignment might be showing the effects of organization at the subatomic quark-ian level.

Not knowing is intimate to believing that an outcome can be open-ended.

/speculation/    We may not need to look in a subatomic explosion to find the boson or God particle. The scientist standing behind the safety glass has been found to direct the outcome of particle/energy wave experiments. Thought influenced whether the mass would be energy or particle.

If we think positive then the placebo, healing effect, averages 38% with no other medicine involved. The reverse is also true (no statistic on hand though). The nocebo response refers to negative responses that occur when an inactive substance is given to a control group in research. The negative or positive effects occur at the individual level, one person might experience positive effects from an inactive placebo while another experiences negative effects from the same inactive substance. The placebo and nocebo effects are not well understood at this time, more research is needed.

Meadow flowers, captured by solar energy.

An excerpt from a lecture about sitting zazen, a type of meditation, titled, “A Natural Action,” by Abbess Zenkai Blanche Hartman,

“We want to attune ourselves carefully to our body and mind so that we can notice when we are out of line with our deepest intention, so that we can feel it when we are out of line with our deepest intention. We want to cultivate that intimate knowing without words and ideas, that intimacy with our self, so that we can tell if we are living our life the way we really want to.”  ____   [http://www.chzc.org/hartman3.htm]

The intestinal tract has brain cells that send information to the brain but not in a vocalized set of data. Emotions and information about allergens and pathogens and the state of the seasonal food supply may be included in the neuron signals from the GI tract. A gut instinct is very real at a biologic and cerebral level but not at the neocortex style of verbal thought. Learning to recognize and understand the difference between the gut sinking, big mistake feeling from the excited new love, twitterpated feeling can help in life.

When the timing is right it may feel right at a gut level. The moist spring air might remind the subconscious of previous fun bike rides. The fresh smell might lead right to getting the bike tuned up and out on the road without ever verbally saying out loud “I plan to ride my bike today because the air smells of springtime.” Tuning in to hunger and fullness signals isn’t always about eating or drinking. The gut knows more than we realize. There are more neurons in the intestinal tract than in the spine or rest of the body (except the brain). Thinking about a snack yet?

***The article suggests that psychiatrists may need to treat this second brain (the GI tract) as well as the regular brain. Talk therapy would be a challenge and more pharmaceuticals won’t really nourish the miles of intestinal tract like food could. The benefit of sitting meditation is the time of stillness to slow down and consider what the twinges at an emotional level might be trying to say about real world events.

Gut knowledge can be very informative but it can be very wrong/misunderstood. Like blogs and anything – think twice, act with care. Pain and discomfort is the body’s signal that something happening is wrong and should be changed. Blocking pain regularly blocks the wisdom that could help heal the underlying problem.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.