Tag Archives: cancer

Mitochondria, P53, cancer and magnesium deficiency

Addition, 7/21/16, there is more information about mitochondria and chronic illness at this link: https://www.sott.net/article/321987-Thanks-Big-Pharma-for-the-Mitochondrial-collateral-damage, the site also has a few other articles on the topic which I haven’t read yet and the topic of magnesium doesn’t come up until you reach the comment that I added. I will have to read more about this topic. Medications that cause an imbalance in calcium and magnesium could be causing stress to the mitochondria and lead to their death and to chronic illness.

  • This article is short introducing a long video. A quote from the short text does mention nutrient deficiencies can be involved, “Nutrient deficiencies are a contributing factor to mitochondrial dysfunction. ” https://www.sott.net/article/308212-Mitochondrial-dysfunction-GMOs-Glyphosate Glyphosate  Inhibition of vitamin D metabolism could lead to magnesium and  calcium imbalance which could be stressing mitochhondria and lead to chronic illness.
  • An abstract with a link to the full text: https://www.sott.net/article/264786-Oxidative-stress-mitochondrial-damage-and-neurodegenerative-diseases
  • https://www.sott.net/article/294075-Fibromyalgia-as-a-mitochondrial-disorder
  • I haven’t watched the video or read all of the articles yet but fibromyalgia is what I had symptoms of that were bad enough to lead to my giving up wheat and gluten products initially. It simply hurt too much when I ate them. And I got better without gluten. Maybe it was the gluten or maybe my genetics with errors in the vitamin D metabolism. I will have to get back to this topic but I share the information now because pain hurts and if even one person is helped then I would be glad. *And I was a professional gourmet baker, I know how to make from scratch croissant, and French baguettes and loaf breads of many types as well as cookies and quick breads. I love wheat products but they didn’t love my body.

A comment of mine that is awaiting moderation posted on another site:

Mitochondria need lots of magnesium (and magnesium is also necessary for white blood cells to be able to perform apoptosis.) “Additionally, exposure to low Mg upregulated plasminogen activator inhibitor-1 (PAI-1) [24]. PAI-1 is considered not merely a marker of senescence, since it is both necessary and sufficient for the induction of replicative senescence downstream of p53 [27].” by D. Killilea and J. Maier, “A connection between magnesium deficiency and aging: new insights from cellular studies” Magnes Res. 2008 Jun; 21(2): 77–82. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2790427/ Please U. of Penn. researchers, look into preventing cancer by providing mitochondria with a healthy diet instead of by providing them with some sort of pharmaceutical designed to manipulate P53 — just prevent P53 from being induced by providing adequate magnesium to the cells. Thanks.

The comment is in response to this article which is about recent animal based research that suggests that a cell’s mitochondria when under stress may produce a chemical (P53) that may lead to cancer: http://scienmag.com/penn-team-finds-mitochondrial-stress-induces-cancer-related-metabolic-shifts/#comment-7188

Now I know mitochondria need a lot of magnesium so one search led to the link in the comment and ~391,000 other links, https://www.google.com/webhp?sourceid=chrome-instant&ion=1&espv=2&ie=UTF-8#q=mitochondrial+stress+P53+calcium+magnesium, including this one:

by Giorgi C., et. al., “p53 at the endoplasmic reticulum regulates apoptosis in a Ca2+-dependent manner” PNAS, Feb. 10, 2015, vol. 112, no. 6, pp 1779–1784. http://www.pnas.org/content/112/6/1779.full.pdf

Apoptosis is the method by which white blood cells are able to kill infected or malfunctioning or old cells. Calcium and magnesium are both electrically active and can both act as signals to promote different types of cellular actions. Magnesium is most active within cellular fluid and calcium entry into cells is limited in part by ion channels that are powered by magnesium. So a magnesium deficient cell can allow too much calcium to enter the cell and within the cell calcium can cause a variety of actions and can even over activate the cell to the point of cell death. (155,000 search results for “excess calcium overworks mitochondria” :   https://www.google.com/webhp?sourceid=chrome-instant&ion=1&espv=2&ie=UTF-8#q=excess%20calcium%20overworks%20mitochondria  and which includes a link about the nerve degeneration disease ALS: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933290/  so it looks like if I want to protect myself from cancer or ALS I should not stress out my mitochondria by maintaining a good intake and internal balance of both magnesium and calcium.)

Another addition to look into more at some point – P53 and apoptosis has been found to be affeected by treatment with a homeopathic preparation (which would be a completely non-toxic energy based treatment. http://www.jcimjournal.com/articles/publishArticles/pdf/S2095-4964(16)60230-3.pdf

/Disclaimer: This information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./

Iodine deficiency and PCOS

Polycystic Ovarian Syndrome is an inaccurately named chronic condition that used to be rare but now may afflict 1 in 15 women. [1] It is inaccurately named because it can also affect men — who don’t have ovaries. I’m having trouble finding the link that I’m thinking of but hypogonadism can occur in men and women. [see below, 3, 4, 5, 6]  Gonadotropin dysfunction and insulin resistance seem to be consistently involved in the problem for women. It is a common cause of infertility and may affect 6% of women. [7] PCOS in women is actually a syndrome that is cause by an imbalance in the pituitary gland of the brain which causes increased androgen production in women.

The current mainstream medical consensus is that the cause of the syndrome is unknown. However the condition is closely associated with iodine deficiency. While iodine is best known as a mineral necessary for the thyroid gland but it is an essential nutrient for the ovaries, mammary glands, prostate and the endocrine glands.

Iodine lack is known to be a factor in the development of breast and prostate cancer. Sixty patients with a variety of cancers were studied. All sixty patients were found to have serious iodine deficiency.[2]

Continuing to claim that the cause of conditions is unknown perpetuates inaccurate treatment by the mainstream medical community while denying patients a simple cost effective treatment of the actual underlying cause of their symptoms. And cancer risk may be increased if the underlying nutrient deficiency is left untreated or is only treated with thyroid hormone if hypothyroidism. Providing an external source of thyroid hormone helps some symptoms of hypothyroidism but would leave the rest of the glands in the body undernourished if the condition is due to low iodine and/or elevated levels of bromide, chloride or fluorine.

The pancreas is also a gland [8] and insulin resistance in PCOS could be due to iodine deficiency in the pancreas causing insulin resistance that leads to gonadatropin dysfunction. One of the hormones produced by the pancreas is insulin. Glucagon is the other hormone produced by the pancreas. Both are involved in control of blood sugar levels. Insulin helps cells take glucose in and glucagon signals the liver to make more glucose out of glycogen, a longer chain form of carbohydrate that contains the individual molecules of glucose.[8] Levels of glucagon like peptide 1 (GLP-1) were reduced in patients with PCOS. Decreased incretin production may be involved in the insulin resistance seen in patients with PCOS. [9] Incretin refers to a group of hormones that include GLP-1. They help lower blood glucose levels by signalling the pancreas to make more insulin. [10] So maybe dysfunction of the pancreas or dysfunction of the insulin being produced is an underlying problem.

Iodine is chemically very similar to bromide, chloride and fluoride except that the iodine makes functional thyroid hormone. Bromide, chloride and fluoride can be taken up by the gland and incorporated into hormone production but would produce a hormone that might show up on a lab test as present but is dysfunctional within the patient who continues to experience negative symptoms of hypothyroidism — how do I know — first hand experience.

My symptoms of hypothyroidism went away after using a high dose iodine supplement. It is considered a risk by the mainstream medical system because it can cause hyperthyroidism in some patients — which I also learned the hard way but I stayed on the high dose supplement too long and wasn’t aware of the need to take selenium at the same time. Selenium is used in the enzyme that helps break down excess thyroid hormone. I’m doing better now with stable thyroid hormone levels and an overactive thyroid that remains stable when I avoid certain foods and iodine sources. The undiagnosed hypothyroidism and fibrocystic breast pain went away with the iodine supplements and decreasing levels of bromide, chloride and fluorine may also have helped reduce risk for breast cancer or other cancers.

So learning things the hard way isn’t the easy way to learn but as Francis Bacon (1561-1626) famously said, “Knowledge is power,”  and I would rather have healthy thyroid function then unhealthy function or no thyroid gland at all. (The standard treatment for hyperthyroidism is to treat it with radioactive iodine to decrease function or to surgically remove it. But autoimmune hyperthyroidism is actually a bone marrow problem that attacks the thyroid and other areas of the body and the radioactive iodine treatment can increase risk to the other areas of the body.) Having learned things the hard way makes me more motivated to try to share information so that other patients can get help that helps rather than harms or who get the message that I kept getting – your lab tests are normal so you must be healthy and your symptoms must be psychosomatic (all in your head) so go see a therapist and talk about your troubles there — no help, dismissive, and disabling — that type of message encourages the patient to ignore the symptoms that they are sensing and to simply consider themselves as crazy.

Radioactive iodine causes thyroid cancer and the best protection against it is being sufficient in iodine before being exposed to radioactive iodine and the next best protection is taking high dose iodine during a radioactive iodine leak. This was learned by the suffering of people living around the area of Hanford, Washington State, U.S. where radioactive materials were being produced for the bombs used on Hiroshima and Nagasaki, Japan during WWII. The people of Hanford weren’t told about the protective benefits of iodine however. They eventually received some money from the government in settlement payments but it took many years and lawyers may have received more money from the government .

There are still 1900 corroding barrels of toxic waste in the Hanford, WA area slowly leaking into the ground soil and placing a nearby river at risk and as it empties into the Pacific Ocean, also placing the ocean at risk of radioactive contamination. Leaks occasionally expose workers there to increased danger. The level of radiation overall is no longer a direct risk to citizens living in the area but the barrels need to be stored in better containers for long term safety.

Radioactive iodine is used in X-ray machines and being iodine sufficient makes the radioactive iodine X-ray work less well — but I would rather have citizens bodies work better and prevent thyroid cancer in the first place rather than promote iodine deficiency because it makes X-ray machines more effective. [“First do no harm,” – unrelated to PCOS, a benign type of thyroid nodule that has been routinely treated as cancer has a medical team trying to get it renamed and treated as the benign nodule that it is: It’s Not Cancer: Doctors Reclassify a Thyroid Tumor.]

This wasn’t the topic I meant to write about when I sat down this morning but my search engine turned up link [1] by accident and I wanted to save it — and I wrote a few additional notes on the topic. Consider it a Mother’s Day gift for the 1 in 15 or 6% of women who may be infertile due to iodine deficiency but who are unlikely to be informed of the potential benefits of iodine by the current medical system. Adequate iodine levels during pregnancy may also help protect the infant from autism developing later in life and from congenital hypothyroidism. See previous posts for more information on Preventing autism perinatally – before conception, (Dec. 22, 2015) [11], and the benefits of iodine for preventing congenital hypothyroidism. [12]

Making an educational website for perinatal health education has been on my to-do list since December and I finally bought a domain for the purpose. That is wrapped into the other topic I meant to write about this morning — slow but steady may not always win races but progress is progress.

/Disclaimer: Opinions are my own and  the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes./

  1. “Iodine and Polycystic Ovary Syndrome (PCOS): What You Need to Know,” Dr. Edward Group, [http://www.globalhealingcenter.com/natural-health/iodine-polycystic-ovary-syndrome-pcos/]
  2. Cancer and Iodine *Still under construction,”[http://www.theiodineproject.webs.com/cancerandiodine.htm]
  3. Pituitary and testicular function in sons of women with polycystic ovary syndrome from infancy to adulthood. Recabarren SE, et, al., J Clin Endocrinol Metab. 2008 Sep;93(9):3318-24. [http://www.ncbi.nlm.nih.gov/pubmed/18544620]
  4. Male hypogonadism: an extended classification based on a developmental, endocrine physiology-based approach. Rey, RA, et al.,  Andrology. 2013 Jan;1(1):3-16.  [http://www.ncbi.nlm.nih.gov/pubmed/23258624]
  5. Polycystic ovaries in patients with hypogonadotropic hypogonadism: similarity of ovarian response to gonadotropin stimulation in patients with polycystic ovarian syndrome., Shoham, Z, et al., Fertil Steril. 1992 Jul;58(1):37-45. [http://www.ncbi.nlm.nih.gov/pubmed/1624021]
  6. Androgen deficiency, Wikipedia.org, [https://en.wikipedia.org/wiki/Androgen_deficiency]
  7. Polycystic Ovary Syndrom: It’s Not Just Infertility, Hunter, MH and Sterrett, JJ.,

    Am Fam Physician. 2000 Sep 1;62(5):1079-1088, [http://www.aafp.org/afp/2000/0901/p1079.html]

  8. Medical Terminology for Cancer, 12: The Endocrine System (Hormones),[http://www.cancerindex.org/medterm/medtm12.htm]
  9. Fasting and post-prandial glucagon like peptide 1 and oral contraception in polycystic ovary syndrome. Aydin K., et al., Clin Endocrinol (Oxf). 2014 Oct;81(4):588-92. [http://www.ncbi.nlm.nih.gov/pubmed/24730585]
  10. Incretin, Wikipedia.org, [https://en.wikipedia.org/wiki/Incretin]
  11. Preventing Autism Peri-natally – Before Conception, December 22, 2015, [http://transcendingsquare.com/2015/12/22/preventing-autism-perinatally-before-conception/]
  12. One billion IQ points and Iodine, March 9, 2015, [http://transcendingsquare.com/2015/03/09/one-billion-iq-points-and-iodine/]

A preventative health longevity study could be crowd sourced

Clinical research trials with actual patients have to address the ethical concerns of using an experimental treatment instead of a treatment that has become the accepted standard of care. Longevity studies start with healthy people. Measurements and health history data are collected at the beginning of the study and then periodically more data about health habits and lab measurements are collected. Eventually, five or ten or twenty years later, the data is grouped to see how many people ended up with negative health diagnoses and whether those smaller groups of people had any lifestyle or dietary choices in common.

It took many decades but eventually enough data was collected to show that cigarette smoking is a significant negative health risk, maybe not for every single smoker but enough of them got sick that eventually the activists in support of preventative health were able to get the message out that cigarette smoking is dangerous to individuals, not just profitable for cigarette companies.

The more recent research on diet and cancer showed that less animal products makes a difference in the amount of a cancer promoting chemical, IGF-1, that is produced by a person. So an exclusively vegan diet or vegetarian diet might be a better cancer prevention diet but simply having more beans and produce and less meat, eggs, and dairy products might also help prevent cancer. A crowd sourced research project could be based on an internet app that allows individuals to enter and track their daily meals and any supplements or medications they use regularly. The app could provide the individual with information about their calorie intake or protein, fat, and carbohydrate intake, or a micro-nutrient. The dietary and lifestyle data would be collecting over time and eventually could be available to researchers interested in looking for specific types of diseases or lifestyle or dietary patterns associated with the people who eventually got that type of disease.

An example might be black hair dye which has been associated with an increased risk of cancer, [1] , so five or ten years into the study a researcher might pull up all the participants whose data mentions “got my hair dyed black today,” and see how many of them developed cancer during that time period and then compare them to all the participants whose data mentions “got my hair dyed _some other color_ today,” and to all the participants whose data never mentions hair dye at all or better yet, who answered “No” to the specific question “Do you ever get your hair dyed at a hair salon or at home?”  — Yes or No.  If you marked yes what color did you choose to dye your hair today?_click which color you chose today —.

Maybe black hair dye is really more of a risk when you also smoke cigarettes and/or also eat a diet with animal products or are also exposed to hazardous chemicals in your work environment. Maybe black hair dye is only a risk for people who choose black hair dye many times over the years rather than only one or two times. Maybe it’s only a risk for the people who chose it many times and who smoked cigarettes or ate animal products frequently or who chose black hair dye and worked in an environment with other toxic chemicals. We don’t really know unless we collect the data as it is happening rather than trying to ask people about their habits years later.

A large crowd sourced longevity study could collect data about people’s personal lifestyle habits and about their work or recreational environments. A smartphone app could provide the individual user with some feedback about the data they had entered, such as a calorie count for the day, and all of the entries from all of the crowd would be collecting for research scientists to eventually collate and look for patterns of habits or environmental hazards that were associated with less risk for the participants and those that were associated with increased health risks.

Keeping people’s data secure and private would be a concern but there’s probably already apps for that — a crowd sourced research project would require software experts and health experts. Prototypes for crowd sourced research do already exist in the area of gene mapping. A dietary focused longevity study that was working in conjunction with the gene-mapping research groups could be even more informative for both groups, down the road a few years.

There is good news from Australian researchers who have modified a type of algae into nano-particles that are able to carry chemotherapy drugs specifically to the cancerous tumor and to avoid healthy cells. This would make the toxic chemotherapy drugs much less harmful to other rapidly growing cells and would reduce the negative side effects caused by the death of the rapidly growing intestinal cells and hair follicle cells.

  • Targeted drug delivery using genetically engineered diatom biosilica,” [nature.com] Bahman Dalalat, et. al., Nov, 10, 2015

This post is a continuation of two earlier posts, or maybe three:

  • “Accidents don’t happen,” – if they can be prevented
  • Evidence based medicine: is the evidence to support the use of patent medicine?

/Disclosure: This information is provided for educational purposes within the guidelines of fair use. Information is not a substitute for individual health guidance. Please see a health professional for individual health care purposes./

Evidence based medicine: is the evidence to support the use of patent medicine?

The underlying problem with a for-profit health care industry is that a primary focus has to be on finding medicines and surgical devices that can be patented and sold for a profit rather than focusing exclusively on finding out how to prevent disease or restore healthy function. Finding out how the body works during health and sickness and finding out how to restore health using natural strategies is not as profitable because natural strategies are usually not something that can be patented and sold at a steep mark-up.

Natural processes of the body are studied in health and sickness with the stated goal of learning how to restore health but too often there is also an underlying and unspoken goal to restore health but only with a product that can be patented and sold at a markup. Foods and vitamins and natural hormones can not be patented and therefore it is less profitable to use them as treatments — there is less of a price mark-up.

As most people involved with primary prevention in public health know all too well, prevention is often under-resourced in public agency budgets and virtually non-existent in the private for-profit sector.

The President of the Institute of Medicine, Dr. Harvey Fineberg, addressed this in a 2006 lecture at the UCLA School of Public Health entitled “Why Prevention is a Hard Sell.”146 He listed some of the reasons as follows: “There is no drama in prevention; non-events are not counted; statistical lives don’t have immediacy; prevention is not profitable; prevention often runs against commercial interests; it may conflict with personal preferences or religious beliefs; and there is declining trust in leaders and institutions, challenging people’s willingness to follow guidelines.”

A Forbes magazine story in 2004 quoted a clinician at a cancer treatment center in New York as saying that ten years earlier, he could extend the life of one of his patients by 11.5 months on average with a drug that cost $500; in 2004, he could extend the life of a patient with the same diagnosis 22.5 months, at a cost of $250,000. The goal of many current cancer treatment protocols is to repeat this experience with more and more types of cancer. [1 

Vegetarian and vegan diets have also been associated with fighting cancer — but by reducing the amount of cancer promoting chemicals (IGF-1) in the person’s blood. Vegans had less of the cancer promoting chemical than vegetarian diners, who had less than people eating a meat based diet.

“Women placed on plant-based diets for just two weeks, for example, were found to suppress the growth of three different types of breast cancer (see images of the cancer clearance).” “Similar results were found for men against prostate cancer (as well as against prostate enlargement).” [2]

Fighting cancer by preventing it from happening in the first place could extend a person’s lifespan far more than 22.5 months and without causing severe vomiting or hair loss, and at a much lower price than $250,000, and without potentially causing cognitive decline. The bad news is that cognitive decline is common among breast cancer survivors and the good news is that the decline tends to improve somewhat between 18 months and 36 months after treatment, (less of an improvement was seen in survivors with multiple diagnoses). [3]

However news that a vegan diet stops production of a cancer causing chemical from forming in a person’s blood would probably not be good news for the person who would rather be told that their cancer was a complete mystery which probably had nothing to do with the person’s lifestyle or their food preferences and that some medication, or surgery, or radiation, or a combination of all three, would take care of the problem without the person having to change a thing about themselves — except that that isn’t really true. Some of the treatments might make all food taste metallic, and some may cause severe vomiting which might leave the person not wanting to eat anything at all and may leave them with some lasting food aversions depending on what they were eating before the severe vomiting stage was reached — the dietary recommendation is to plan ahead for the nauseous stage and to eat something anyway because nutrients are still important but choose nutritious foods that aren’t also favorite nutritious foods for meals that are likely to be coming back up again in a short while. A vegan diet, on second thought, probably tastes better than having a metallic taste in the mouth, or worse.

And it doesn’t even have to be a vegan diet — vegetarian diets that include fish have also been found to reduce cancer risk, [7] — but the information about either study wasn’t in mainstream news outlets. I found the information on virtual news websites — so this is basically top secret news — the cure for cancer has been in the grocery store this whole time — just avoid the meat aisle and maybe the egg and dairy cases and spend more time in the produce section.

It can be a career risk to write about less profitable health treatments. The paragraph about cancer treatments and the 50,000 percent increase in price that occurred over ten years, that was excerpted earlier in this post, concludes with the following statement: “Those who seek to prevent or reduce the magnitude of these profits risk being swept aside by industry representatives and their political and scientific spokespeople.” [1]

Ginger has over 400 active phytochemicals and humans have been enjoying it for thousands of years — the long term evidence is in on ginger – people keep growing it because they like it — either they like its flavor or its effects or both. [4] Some of the active phytochemicals in ginger have been found to help reduce arthritis pain as much as the anti-inflammatory pain-killing medication ibuprofen (approximately a 1/2 teaspoon dried ginger powder per day). And even better pain control was found when ginger was used in combination with ibuprofen. Ginger also helps protect against ulcers while long term ibuprofen use can be damaging to the GI tract. And more recently another phytochemical found in ginger, 6-shogaol, has been found to help kill breast cancer cells while at the same time not being harmful to surrounding healthy cells. This is early research rather than clinical trials. [4, 5] The negative side effects from most cancer treatments are usually because the treatments are harmful to both cancer cells and to health cells that grow rapidly.

Ginger has few negative side effects compared to chemotherapy or even ibuprofen. The two risks that I am familiar with: 1) Eating large amounts on a daily basis may increase risk of bruising and  bleeding too easily as ginger has blood thinning activity. A half teaspoon of dry powdered ginger per day was the dose found helpful for reducing arthritis pain. I have experienced easy bruising when I was using more than the half teaspoon of powdered ginger on foods, I was also eating chunks of candied ginger regularly and was also using raw ginger in cooked dishes in large amounts. I haven’t had problems with easy bruising when eating only the half teaspoon per day dose.   2) Small amounts of ginger during pregnancy is probably fine and active phytochemicals in the root vegetable may be helpful for reducing nausea, (Folk wisdom example: Gingerale for nausea), but very large quantities of ginger on a regular basis during pregnancy  may increase risk of miscarriage.

I didn’t find the ginger powder/ibuprofen study citation when I looked for it, but while looking I did find a more recent study done on cell cultures that found ginger extract effective for reducing cytokine production in Rheumatoid Arthritis (RA) and Osteoarthritis (OA). [6]

In a for-profit industry too often the goal of research is to find a chemical that is effective for some health condition, like 6-shogaol, and then to find a way to chemically make it unique and therefore able to be patented and sold at a larger markup than would be possible for a produce item like ginger root, but without ruining the original chemical’s effectiveness and without making the new chemical too toxic. That can be a risk when fluoride or bromide is added to a medication; the heavy metal can help the medication enter cells — which can make it a more effective or a faster acting medication — but then the atom of fluoride or bromide is not easy for the body to remove from the cell and the heavy metals may be increasing long term health risks. [8]

My goal in sharing health information is twofold —

— For the general reader who is interested in science and alternative health information: writing easy to read summaries of health information for the individual reader is where I have training and experience. As a patient I am looking for health guidance for my own conditions but as a dietitian I also am interested in learning more about all aspects of health and illness. The entire body needs balanced nutrition in order to function and therefore a dietitian specializes in understanding all of the body’s systems and how they interact.

— For the open-minded science reader: some people read summaries and other people read reference lists. Frequently cited papers or books would be immediately recognized by some readers and they might be interested in clicking on other links that they hadn’t seen yet, or hadn’t seen in relation to the rest of the list. Some readers might read the summary in seconds and skim through the links in a few minutes — and gain ideas for their own research — that is my hope. In some places there may be more funding, and more academic freedom, and more interest in preventative health care, and more interest in the use of natural products for restoring natural function, — I can dream and read and share. Some comments that I’ve received do suggest that at least a few people appreciate my posts for providing research ideas.

/Disclosure: This information is provided for educational purposes within the guidelines of fair use. Information is not a substitute for individual health guidance. Please see a health professional for individual health care purposes./

  1. Richard W. Clapp, DSc, MPH, Molly M. Jacobs, MPH, and Edward L Loechler, PhD, Environmental and Occupational Causes of Cancer New Evidence, 2005–2007, Rev Environ Health. Author manuscript; available in PMC 2009 Dec 10., [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2791455/]
  2. Kathy Freston,  A Vegan Diet (Hugely) Helpful Against Cancer, 12/09/2012 [http://www.huffingtonpost.com/kathy-freston/vegan-diet-cancer_b_2250052.html]
  3. Zheng Y, et. al., Long-term cognitive function change among breast cancer survivors., Breast Cancer Res Treat. 2014 Aug;146(3):599-609. doi: 10.1007/s10549-014-3044-1. Epub 2014 Jul 9. [http://www.ncbi.nlm.nih.gov/pubmed/25005574]
  4. Ginger: 10,000x Stronger Than Chemo (Taxol) In Cancer Research Model, Nov. 7, 2015, [http://healthimpactnews.com/2015/ginger-10000x-stronger-than-chemo-taxol-in-cancer-research-model/]
  5. Anasuya Ray, Smreti Vasudevan, Suparna Sengupta, 6-Shogaol Inhibits Breast Cancer Cells and Stem Cell-Like Spheroids by Modulation of Notch Signaling Pathway and Induction of Autophagic Cell Death., PLOS One, September 10, 2015, DOI: 10.1371/journal.pone.0137614 [http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0137614]
  6. Søren Ribel-Madsen, et al., A Synoviocyte Model for Osteoarthritis and Rheumatoid Arthritis: Response to Ibuprofen, Betamethasone, and Ginger Extract—A Cross-Sectional In Vitro Study., Arthritis. 2012; 2012: 505842. 2012 Dec 31, [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546442/]
  7. Jennifer Lea Reynolds, Vegetarian diet reduces cancer risk by up to 43% in new study., Nov. 6, 2015,   [http://www.naturalnews.com/051856_vegetarian_diet_colorectal_cancer_fish.html#]
  8. by me, “Private: Eicosanoids are made from eCBs from the membrane,” *This is one of my older posts with more excerpted material and a messier format so I have it closed to public view. The post does include more information on the health benefits of ginger for preventing colorectal cancer and prostate cancer. Ginger extract seems to help prevent cell membrane/endogenous cannabinoid breakdown and reduce the release of metabolites of endogenous cannabinoids (eCBs) — which include eicosanoids and arachidonic acid. The pharmaceutical industry charges $2,945 for 1 mg of eicosanoids which we would be able to make for ourselves in the amounts that we need if we are healthy and well nourished. Eicosanoids are also a natural chemical so I’m not sure why it can be sold or how the patent process works in the pharmaceutical industry.


Sea squirts are similar to white blood cells

From an old post of mine (Jan 10, 2012):

White blood cells need plenty of magnesium to do the work of apoptosis – hunting down, killing and engulfing the waste left over from decaying normal cells (in need of recycling), or infected or precancerous cells (to be reduced and reused).
The immune function of seq squirts was found to be compromised by copper sulfate, creosote (found in wood treated to be water resistant) and TBTO (found in marine boat paint). Sea squirts are a very basic life form that may move and perform similarly to white blood cells – which are our mobile work force for repair and growth of new tissue and for killing and removing old, infected or pre-cancerous tissue.

Addition (Sept. 9, 2014): Tunicates, also known as sea squirts, have made it into the news because they may have anti cancer properties [1] and they are one of the simplest life forms with cannabinoid receptors. [2]

Research into the effectiveness of drugs for Alzheimer’s Disease has also occurred using tunicates. They are said to be our closest invertebrate ancestors with about 80% of their genes being similar to human genes. Inserting a misshapen protein from a patient with a hereditary type of Alzheimer’s Disease was found to start a rapid change in the structure of proteins in the tunicates within one day. So tunicates can be very rapidly made sick with symptoms that are similar to Alzheimer’s Disease. That makes them more useful for testing new drugs for Alzheimer’s Disease than other types of larger vertebrate animals used in medical research. [3]

Tunicates help clean the water supply but they can also be made sick by toxins in the water. Pollution isn’t just bad for humans or just bad for today’s humans, it is bad for everything, and will be for centuries. — The take home point is that if copper sulfate, creosote and TBTO are bad for sea squirts then the pollutants are likely to be bad for us too, — we are distant cousins after all, 80% related at least.

/Disclaimer: Information presented on this site is not intended as a substitute for medical care and should not be considered as a substitute for individualized medical advice, diagnosis or treatment. See a health professional for personal health care needs./