Marginalization and violence

*Additional note – this post is not about me or a specific group or any individual in particular but is about all those observing and the affects they may face. People have to go along with a group but it can leave them psychologically uncomfortable. And someone who is already being persecuted too may be less likely to feel hope and more likely to feel even more worthless – the goal of those doing the marginalization.  All I’m suggesting and asking possibly, is tone down the volume of the jokes and dislike of each other because that in itself may be increasing risk of random violence anywhere and everywhere.  This post is simply about the repercussions, the ripple effect for observers – please think about the other marginalized people who may see the extreme treatment of some as a reason to give up.

I’m adding a section from a project I’m working on that is about transference and countertransference and working with others without getting too involved and a quote by Abraham Lincoln who encourages us “to act in the interest of peace.” This is like giving you the solution to a problem first and then giving you the problem but since it is about a severe problem maybe it may help to first have a solution in mind before reading about the problem.

“With Charity to All.”

“Enough lives have been sacrificed; we must extinguish our resentments if we expect harmony and union.  We must now begin to act in the interest of peace. With charity to all.” – Abraham Lincoln, to associates regarding letting Civil War leaders leave the country rather than be caught and executed. (pp23-24, Lincoln)

11.4.4. Transference and Countertransference – getting too involved.

Successful leaders and mental health counselors don’t let someone else’s bad day ruin their own good mood.

If as a modern business our goal is to overcome these natural instincts to trust those and want to be led by those who are more similar to ourselves than those who are different, then first it is necessary to simply admit that the instincts exist instead of suggesting that simply saying we are “equal” truly can make us equal to each other at an instinctual level. Remember we don’t have to emotionally “feel” like family or best friends in order to complete a project with someone. Advice from successful leaders suggests not taking it personally, don’t let your own emotions be affected by another person’s mood, and remember that even difficult people can add value to a team.

  • Read more, a list of tips for a business reader regarding how successful leaders cope with working with people they don’t like: 11 Ways Successful People Deal With People They Don’t Like. (11.21)   

Transference and countertransference of mood and symptoms is seen in the field of psychiatry and mental health counseling. The patient and counselor may form emotional patterns learned in their childhood and negative symptoms may develop in the counselor. The theory may apply to long term relationships formed in other areas of life:

    • Read more: The Space Between: Transference and Countertransference (11.22)
    • Transference and Countertransference: A Common Sense Perspective, includes exercises to help a person become more aware of their own body tension or relaxation and other responses that occur naturally during a conversation. We tend to “mirror” each other’s body language and style of speaking without being consciously aware of the tendency. The physical tension however can have very real effects on our mood. (11.23)
  • Transference and Countertransference in Cognitive Behavioral Therapy, is a journal article with examples of scenarios and clinician responses: (11.24)

11.4.4.1: Social workers are less likely to commit suicide than physicians.

Social workers may commit suicide less often than physicians due to a difference in training about self care. Social workers are reminded to not become overly invested in the job or with a particular client’s troubles by having balance in their other roles in life. It did not seem to me that I was as good as the social workers whom I worked with at balancing my own life roles, but having role models who were good at it and who reminded me that it helps to have balance and variety in life, did help to let me know what is possible and worth working towards as a goal.

11.4.4.2: Resources for help or just someone to talk to:

  • U.S. National Suicide Prevention Hotline: Call 1-800-273-8255, Available 24 hours everyday. (I.suicidepreventionlifeline.org)
  • National Helpline: Substance Abuse and Mental Health Services Administration: “SAMHSA’s National Helpline, 1-800-662-HELP (4357), (also known as the Treatment Referral Routing Service), is a free, confidential, 24/7, 365-day-a-year treatment referral and information service (in English and Spanish) for individuals and families facing mental and/or substance use disorders.”  (I.samhsa.org)
  • Rape, Abuse and Incest National Network, RAINN Hotline: 1-800-656-HOPE, (I.RAINN.org)
  • Child Welfare Information Gateway: a variety of toll-free hotline numbers for concerns involving the safety of children. (11.18)
  • Power and Control and Equality Wheels  The following training materials are for helping victims of domestic violence and batterers learn how to recognize problem behaviors but emotional manipulation or abuse of power and control can occur in many types of relationships not just between couples.The Power and Control Wheel (11.15) was developed by the Domestic Abuse Intervention Programs (DAIP). (11.16) Manipulative behaviors are grouped into eight categories in the model. An additional Equality Wheel (11.17) was developed to help guide batterers and victims of emotional or physical abuse towards healthier ways to interact. It is grouped into eight equivalent categories with examples of healthier ways to interact with each other. Problems frequently can involve communication issues by both people in a relationship.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes. The Academy of Nutrition and Dietetics has a service for locating a nutrition counselor near you at the website eatright.org: (eatright.org/find-an-expert)

And a section from G. Relaxation & Stress,  Four: Social contact would help protect against oxidative stress.

Social contact soothes stress and helps prevent children from developing PTSD:

Having a role that fulfills a valued purpose for the group is associated with an increased sense of happiness. Read more: A Better Kind of Happiness, by Will Storr, (G.9). Stress may become more overwhelming however if the person is isolated or never learned social skills or developed enough trust in others to ask for help or seek out help. Children in situations with emotionally immature caregivers may learn that people around them can’t be trusted or that trying doesn’t lead to success so why bother trying – they can learn a sense of helplessness and hopelessness and not even try to seek help because they are unfamiliar with finding strength or support from others.

In the book Adult Children of Emotionally Immature Parents: How to Heal from Distant, Rejecting, or Self-Involved Parents, by Lindsay C. Gibson (G.10) four different types of emotionally immature caregivers are described and how growing up with them might affect children. Solutions are also provided in the form of techniques for how, as an adult, a person might overcome the lessons they learned as a child once they discover that emotions aren’t dangerous things to never be discussed or worse that one might be punished for exhibiting them.

Some emotionally immature people may feel threatened by strong emotions and may react negatively to children who are simply being children. The child in that situation learns to not trust themselves and may not learn that emotions are normal rather than upsetting or frightening.

Severe childhood trauma can lead to changes in the brain that cause ongoing symptoms of Post Traumatic Stress Disorder (PTSD). A new strategy for treating PTSD has been developed which involves electrical stimulation of the vagus nerve called Vagal Nerve Stimulation (VNS).  

The excerpt summary from the book Adult Children of Emotionally Immature Parents (G.10) regarding the research by Stephen Porges suggests that the vagal nerve is the nerve pathway that naturally is stimulated when social contact is sought by mammals who are enduring a stressful situation. (G.11) (G.12Infants and children depend on their caregivers for everything and try to please with their smiles, eye contact, or baby coos. If the infant isn’t receiving eye contact in return however they may stop trying or are scolded they may learn to look away and to avoid eye contact. Children ideally need emotional support in order to develop trust in themselves and in others. Parents who have limited skills in understanding and accepting their own emotions may not be able to teach their children what they don’t understand themselves. Children who have some role model in their lives who understands emotional skills may cope better than children who don’t.

The topic is discussed in more detail in the book Adult Children of Emotionally Immature Parents: How to Heal from Distant, Rejecting, or Self-Involved Parents, by Lindsay C. Gibson, PsyD, (New Harbinger Pub., Inc., 2015, Oakland, CA) (G.10) (This book is not a twelve step book and is not affiliated with the Adult Children of Alcoholic or Dysfunctional Parents twelve step group.) On page eight the author discusses the importance of emotional connection for humans and other mammals for responding less negatively to stress. Stephen Porges published work in 2011 suggesting that mammals evolved a way in which we can get additional soothing during fear situations when we are in touch physically or possibly even mentally – thinking about them during times of need. It involves vagus nerve pathways that can be inhibited to reduce the fight, flight, or freeze stress reaction. (G.10)

**** It is not easy being a parent or a child is what I’ve learned about life.

Original beginning of the post:

Studies on random violence and terrorist acts have found that individuals and groups who are marginalized may be more at risk. Persecution and humiliation and child trauma or neglect was more common in the history of people arrested for a violent crime. The recent death of a peaceful protester in Charlottesville is tragic for the family and community, and the nation. (bloomberg.com/2017-08-14)

We are becoming even more divided since the difficult campaign season but marginalizing young adults may just lead to more violence. A group that has appeared to be supportive of or producing the Nazi themed memes  has a petition up to help save them from oppression, whether it might be satire about saving Pakistan is unclear. (change.org/p/the-recognition-and-freedom-of-the-kekistani-people)

Update, 8/18/2017, I’ve looked into this group further and it does seem to be a satire group whose artwork got taken up by other extreme right wing groups.. Their group’s name and artwork was not visible in any of the video footage that I saw of the event at Charlottesville. And a police officer has stated that the event may have been allowed to happen as a political move to show that the current administration is inciting violence. If the police officer is correct than the Charlottesville administration was the ones inciting it, but they deny it. Snopes has a debunking statement up about the police officer’s claim. Ever since the site debunked a story by suggesting it was simply a math anomaly I’ve been suspicious of their results – yes odd math happens but that is not a “debunking” – you’re not supposed to simply throw out the unusual experimental results simply because they fall at outside of the 98th percentile. See this article:  (yournewswire.com/charlottesville-inside-job) there’s a Snopes factcheck of it that says its false: (snopes.com/were-police-told-stand-down-charlottesville)

Young adults who are just looking for recognition and freedom from “normies” may need more variety of role models to follow. When “normal” society is the bad guy and Trump is the savior figure in the artwork – we all have a problem.

There are a few articles on my website about Zionism and World War II but the information is not in support of Hitler. Anti-Zionists at the time of World War II included Jewish people, such as Albert Einstein. There was collusion between Hitler and the Zionists at the time which may have left more of the non-Zionists Jews at risk for the concentration camps while a few left early for Palestine and they were allowed to take their possessions.  It all may involve banking and the national monetary system that Germany put in place after WWI cost them a large amount in reparations. History is complicated and the winners write the books. (The Israel leader supports Donald Trump, that seems significant: theantimedia.org/israel-trump-relations-important-condemning-nazis)

I’ve been working on a health information website, a directory of links to other resources with narrative about their value. It started out as an example of a policy manual for preventing harassment and discrimination in the workplace.

I’m posting a section regarding random violence and humiliation of others as it seems pertinent to our modern interconnected society. When one is singled out for persecution it is warning all the others in the group and other marginalized groups, that if they aren’t careful then they could get the same treatment – so follow the group’s expectations – their norms, but for the wrong person on the wrong day it might build up to a tipping point and an angry outburst might occur. Plan ahead for a pleasant work environment for employees and customers and have business as usual days instead of a tense environment or one that unfairly singles out certain individuals or groups for mistreatment by having open communication and supportive management. Employees like autonomy – some control over or input into how their jobs are performed.

Policy manuals are boring so that the most exciting event of the year is the company party or the baby shower for so-and-so or the annual fundraiser event or whatever the company thing is – celebrate that and it helps celebrate the whole team.

9.4: “Running amok,” “going postal,” or “a red stapler” moment.

Creating a pleasant work atmosphere where people feel safe from unfair persecution or humiliation may help prevent sudden violence where people who had seemed like quiet average people snap and try to harm others.  

The sudden outburst of violence is not that common and is not about a serial killer who is concealing themselves as average among peers, or the manipulative and charming boss with a narcissistic, sociopathic, or psychopathic side. A random violent outburst more likely might be the hard worker who finally reached a “camel straw” moment – the proverbial final straw added to a load that makes the already overloaded camel’s burden too heavy for it to carry any further.

Verbal and physical intimidation are more common problems in the workplace; and not reporting problems is also common. When is problem behavior serious? Or when is joking and teasing and pranks approaching harassment?

  • More information and guidance about workplace violence, and examples of common situations in Canadian workplaces is available at violenceautravail.ca/Understanding violence.  The site includes a list of “Examples of Workplace Violence:  being threatened with death or injury; getting hit or pushed; having an object thrown at us; being subjected to sexual touching and sexual assault; being scratching or pinched; being spat at; being yelled at; receiving threatening messages or emails; being ridiculed or humiliated; being threatened physically (for example, being shown a fist); having our property damaged. (9.105)

Labeling situations as serious and reportable may help an employee see that what they are experiencing is “bad enough,” and that they should seek help before anything “really serious” happens.    

    Labeling emotions can help to recognize when they are starting to build in one self or others. Unrecognized emotions may be more difficult to control because they are unrecognized but are uncomfortable and may lead to agitation and gradually build to more intense out of control anger or fear.

   “Running amok” is an older term and “going postal,” is a newer term for sudden violence. A “red stapler” moment is a reference to a movie from the 90’s that became an instant classic among disgruntled workers everywhere: Office Space.

  • If you happened to missed it, then if you would just go watch Office Space, “That would be great.” (9.79)
  • Or go read this article about it: 20 Things You Might Not Know About Office Space (9.80)

The movie Office Space shows all the “do not do this to your employees” bad boss examples to avoid following. Don’t be left holding only a stapler, plan ahead and give everyone their own. Fair treatment and a sense of autonomy, a right to some control over one’s work, are important for employees in addition to earning a fair paycheck. Threatening job loss or other retaliations can leave workers feeling trapped and hopeless because they may need that paycheck even if it isn’t fair.

9.5: “Amok” was a medical condition during stressful times.

Research has found that during stressful times, whether due to economic or environmental reasons, people are more likely to act out verbally or physically against people who are not of their same ethnic group. (9.41) During times of stress, violence against women is also more common, particularly against women who are suspected to be sexually active or to have been unfaithful in a relationship. (9.43) Other research has found that the rate of violent crime is associated with the rate of infection in the population. Research into group and individual behavior suggests that the rate of infectious disease in a group is significantly associated with the rate of violent and property crime and with the rate of violent crime against strangers. (9.41)

    It is unclear from epidemiology studies whether an association is causal or correlated, but if health is associated with less violence, it seems like a reasonable goal to promote health and try to prevent infectious disease.     

   Some types of infectious disease can directly lead to symptoms of increased irritability or rage and historically, and times of environmental or economic stress have been linked to a medical condition that was called “amok” where a previously healthy person suddenly started killing or assaulting people randomly. Historically a condition known as amok was first described in 1893 where an individual suddenly acted violently and then would forget the manic episode. Descriptions of the disorder were recorded by the British medical superintendent of the Government Asylum in Singapore. Increases in cases of amok were more associated with “times of social tension or impending disaster.”    

 The term fell out of use as a medical diagnosis but became commonly used in the phrase “running amok” to describe anyone who was acting unusually out of control. 99.42) Gun violence in modern times has involved racist xenophobia or religious ideology in many cases (9.53, 9.54, 9.56), it can also involve copycat reactions to news coverage of other violent offenders, (9.55), and in a few cases may have involved a shooter who claimed to have amnesia of the event afterwards. (9.44, 9.45)     

   Is “amok” a real condition that needs a more modern name? Controlling guns doesn’t control violence with knives or vehicles or explosives or with poisons. Promoting health might help more individuals control themselves.

   Negligence can also be lethal.

   Promoting compassion for others rather than supporting persecution and humiliation of those who are different is necessary. The young learn by observing the way others act and how they treat each other. Teaching compassion or another topic is easier with demonstration than discussion. Police brutality that goes unpunished teaches the wrong message that persecution and humiliation of some types of people is okay when it is done by other types of people. Recently teens filmed a man while he drowned and the group’s laughing and taunting was caught on the audio. The teens never reported the drowning and the man’s body was only found after a missing person’s report was filed. The video later became available and legally it has been found to fall into a loophole in the state’s laws. There is no legal requirement to help a person who is in danger in that state. (9.100)

   Divisive politics and economic hardship can lead to more focus being placed on differences in religion or culture, sexual orientation or gender, between oneself and others but it doesn’t have to. Being civilized can mean recognizing those differences and valuing and seeking to understand them better instead of fearing or mistreating those who are different from oneself.

  • TJ Brown suggests how in a section “Fight for a More Civilized Bigotry,” (pg 14) from a longer article: FEE’s Guide to Keeping Friends Despite Political Differences: How to Have Opinions and Friends (at the Same Time!), fee.org (9.106)

9.6: Gratitude and friendship boost dopamine, so does shaming.

Shaming others, reminding them of guilt, can cause an increase of dopamine in the brain of the person doing the shaming. However a compassionate exchange with a friend or acquaintance can also boost dopamine, and so can reading new and interesting information. Listening to music and enjoying good food can also. There are many positive ways to boost dopamine besides shaming others, such as being grateful for others’ diverse skills and unique backgrounds.

   Shaming others may be a natural instinct to promote one’s own morality by making it clear one is not in support of the topic or person being shamed, (9.21), or it may derive from a sense of guilt about the situation or person being shamed. (9.22)   

    Being fair in the first place would leave less to feel guilty about, accepting each other for our differences as well as our similarities might also.

     Shaming others, purposely humiliating them, can also be a form of control or intimidation to show power over another person or group of people. Shaming one member of a group can serve to humiliate and control the group. Less equal societies, with a group of wealthy elite at the top, may be more likely to use humiliation as a control tactic. (9.81) Human sacrifice in ancient cultures was found in a recent anthropology study to be more common in societies that also had greater inequality between the rich and poor. (9.82)  However, does shaming work as a form of social control to effectively promote changed behavior in the person being shamed?

    The answer is no – or at least not effectively and consistently when it comes to alcohol abuse. Research with reality shows focused on alcohol addiction and recovery have found that alcoholism or relapse were still likely to occur even after public shaming. (9.156)

“The results add to a body of literature suggesting that widely used shaming and humiliating methods of treating alcohol and other drug problems — such as those seen on shows like Celebrity Rehab — are not only ineffective but also may be counterproductive.” (9.156)

“Guilt” is a noun referring to the feeling one feels oneself over an error or misdeed, while “shame” can be used as a noun it is more typically used as a verb, “to shame.” Others shame the one who is guilty or believed to be guilty of something the group disapproves of. Other studies with alcohol counseling individually also found that shaming tactics did not effectively help individuals stop abusing alcohol. (9.156)

      Studies of serial killers and other types of violent offenders found an association with early childhood abuse. Rejection by a parent or other important person in their life was found to have occurred in the early lives of 48% of a group of 62 serial killers in the study. Other types of physical, sexual or emotional abuse such as humiliation have also been associated with violent offenders, and early adoptions, neglect, or abandonment in early childhood have been associated with violent crime. (9.63)

 In a study that included over 1000 violent offenders, shame and humiliation were found to be a common factor; violence was an attempt to restore a sense of pride or self-worth: “In the work, “Shame, Guilt, and Violence,” qualitative data from over 1,000 institutionalized offenders were gathered and analyzed over the course of four decades. According to Gilligan, self-conscious feelings of shame and a deteriorated sense of self-worth are the causal factors underlying violence; humiliation, Gilligan argues, compromises one’s identity, i.e. the way one sees oneself, and leads to feelings conceptualized as a loss of cohesion of the self, or a conceptual death of the self. This leads one to become violent in order to restore pride, or a sense of self-worth (Gilligan, 2003).”  Overcrowding and economic job stress, which leads to lack of parental time, are factors thought to be involved in the number of young men in gangs who may join them seeking the nurturing that was missing at an empty childhood home. (9.83)

If someone at work has a favorite stapler, maybe just let them enjoy it in peace instead of teasing them about it – and maybe get one of your own to find out what the appeal might be. The topic of shame and shaming is continued in the next section, and a therapy method for individuals who suffer from excessive guilt and a tendency to self-shame (9.158) is discussed in more detail.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Is it Addiction or Starvation?

1. Talk Therapy or “Just say no” can’t help a genetic difference.

Talk therapy is also beneficial but can not “cure” a biological difference in metabolism.
  • Looking up the definition of the word “disease” suggests that a genetic difference affecting a body wide receptor system might fit the term “body disease.” “Disease: a disorder of structure or function in a human, animal, or plant, especially one that produces specific signs or symptoms or that affects a specific location and is not simply a direct result of physical injury.” – Oxford Dictionaries (I.1.disease)
Redefining the neurobiological underpinnings and genetic risks of the behavior we call addiction could lead to more targeted help for the sufferers of addiction rather than continuing to treat them primarily by focusing on a discussion of their difficulties with motivation or impulse control.
The Endogenous Cannabinoid System holds answers.
Background information:
  • Endogenous refers to something that can be made internally by our body rather than a chemical that is needed to be obtained from an external source on a daily or semi-regular basis. An example such as oxygen from the air we breathe is needed within every few minutes or cellular damage can start to occur; or trace nutrients such as essential fats or fat soluble vitamins may not be needed as often because they can be stored in the fat and membranes of the body. They may only need to be consumed in the diet every few days or weeks without resulting in negative health effects. The body can store extra vitamin D during summer months that can last most of the winter but does start to run out by springtime.
A person with a metabolic difference due to genetics, chronic illness, or the standard changes associated with aging may need an external source of nutrients that other people of average health would be able to make internally – “endogenously.”
  • Cannabinoids are a type of chemical called phospholipids which are formed from a lipid, a type of fat, and the mineral phosphorus.
I have a genetic difference in my ability to phosphorylate (I.2.wikigenes.BHMT) so that I am unable to make phospholiids endogenously and I have found that having an external source of cannabinoids in my diet every day helps my chronic illness conditions and improves my muscle and nerve control. I am registered as a Medical Marijuana patient in a state where it has been legalized for medical use.
     Some of my symptoms that are relieved by the herbal medicine have been troubling me since I was an infant. I had severe eczema throughout my childhood and severe congestion. Rarely could I breathe through both nostrils and nosebleeds were also common. The enzyme the BHMT gene produces when functioning incorrectly is associated with a risk for vascular problems – ie nosebleeds or easy bruising or spider veins or all of them.
     The protein that the gene normally produces is necessary in Glycerophospholipid biosynthesis, metabolism , and Phospholipid metabolism, (so a double mutation in this gene may make it difficult for me to make phospholipids endogenously), among 17 pathways in all – that is an important enzyme: (I.6.genecards.BHMT) And the CDK-mediated phosphorylation and removal of Cdc6 SuperPath involves 97 other pathways which include a Calcium2+ pathway and a Parkinsons Disease pathway and creatine metabolism (important for muscles) and synthesis of DNA and many other metabolic paths/chains of chemical events : (I.7.genecards.phosphorylation)
  • Phospholipids are found in human breast milk and helps stimulate the infant’s appetite and helps support adequate weight gain. The cannabinoids and phospholipid group perform two main functions – they are flexible and form a significant part of membrane walls, like building blocks or bricks; they can also be released from the membrane and act as messenger chemicals that can activate other systems or be modified slightly to become a different type of messenger chemical called eicosanoids.
  • Eicosanoids include the leukotrienes: Santa Cruz Biotechnology,(I.8.scbt.com)

2. It might be motivating to learn of an underlying cause to cravings.

It might help a person to learn that for a person with a genetic difference, difficulties with motivation or impulse control are likely due to an underlying deficiency of a substance they are missing, which would likely have helped them have better impulse control and to not have cravings for substances.
Someone without the genetic difference would be making the substances internally which would help them have good impulse control and not crave substances.
     Helping the person with substance abuse problems to find approved external sources of the substance (cannabinoids) seems like it would be more helpful and potentially more motivating for them to be able to view themselves as a worthwhile person with special dietary needs rather than as an unmotivated drug addict who just doesn’t try hard enough to change.
     Substance abusers likely quit using and relapsed again more times than anyone cares to count. every single time a chronic user runs out of their substance of choice they are “quitting” until they get more.
     Do you blame a hungry person for eating breakfast in the morning? Should a person just “quit eating” if they have an overeating disorder? Answer: No.
  • Cannabinoids might help some types of eating disorders and some types of drug or alcohol addictions by providing an essential nutrient that the person might not be able to make.
  • If the body can’t make an important substance or convert substances into active forms then it becomes an essential nutrient – essential for that specific person’s daily diet.

3. Genetics of the cannabinoid system and binge eating disorder, alcohol abuse and drug addiction.

“It is important to note that, as with alcohol, marijuana, and heroin, a human genetic variant of the cannabinoid CB1 receptor gene CNR1 has been associated with susceptibility to cocaine and amphetamine dependence (Ballon et al. 2006, Comings et al. 1997; Zhang et al. 2004).
  • Behavioral Neurobiology of the Endocannabinoid System; Ch.13: Drug Addiction, (page 334, I.9.Searchworks)
Endocannabinoids: The Brain and Body’s Marijuana and Beyond is a reference textbook available online as a pdf. (I.10.Endo.pdf)  It includes information regarding the genetic differences known to be associated with binge eating disorder and other drug addictions affected by rimonabant, a chemical which inhibits the endogenous cannabinoid system. Use of rimonabant affected craving for food/sucrose and alcohol in animal research, and it was found to reduce rewarding effects of morphine/opioids, amphetamine, cocaine and diazepam in other studies.
  • Rimonabant is not in use for drug addictions because it is associated with a significantly increased risk for suicide. This is an important point to note – blocking the endogenous cannabinoid system is associated with a significant risk for suicide.
The problem with addiction to some substances or to eating excess food for some cases of over eating disorders is an underlying inability to make the cannabinoids but a remaining need for them and a hunger, an urge for “something,” something that is unknown however. And what people choose to consume in order to try to quench that unknown hunger varies from food and alcohol, to the rest of the drugs that are commonly abused.
     Dietary sources are needed instead. However our food supply has limited sources. Vine ripened produce or lemon oil, rich in aroma, are examples of a food containing cannabinoids or a similar group of aromatic and medicinal phytochemicals called terpenes. Chocolate and the herb rosemary are two other food sources. The spices cardamom, cloves, and nutmeg are also sources. Non-euphoric cannabinoids also exist and may have medicinal benefits depending on the patient’s condition. Copaiba oil is a food grade essential oil that can have non-euphoric cannabinoid content with medicinal benefits.
     Wouldn’t it be nicer to tell starving people that they are starving rather than that they are poorly motivated?
  • For more information regarding binge eating disorder, drug addiction and rimonabant: See Ch.3: Endocannabinoid Receptor Genetics and Marijuana Use, (p72-73 & 91, I.10.Endo.pdf) and Ch.13: Behavioral Effects of Endocannabinoids, mentions that research with rimonabant has helped show excessive alcohol drinking behavior and development of alcoholism may be related to genetic differences in the CB1 receptors. (p319, I.10.Endo.pdf)
  • Impulse control deficits may involve the cannabinoid system: See Ch.13: Behavioral Effects of Endocannabinoids, (pp325-330, I.10.Endocannabinoids.Full Text.pdf).
  • Schizophrenia may be related to a deficiency in the cannabinoid receptors themselves rather than being due to a deficiency in cannabinoids: See Ch.15, Neuropsychiatry: Schizophrenia, Depression, and Anxiety,; of the book Endocannabinoids: The Brain and Body’s Marijuana and Beyond: (p378, I.10.Endocannabinoids.Full Text.pdf)
More recently a gene has been identified in binge eating disorder, the gene for the cytoplasmic FMR1-interacting protein 2 (CYFIP2). (I.11.sciencedaily) The gene has a number of known variations and has allso been associated with Fragile X, an autism like condition, ADHD, autism, obsessive-compulsive behavior, and Prader-Willi Syndrome.. (I.12.ncbi.FragileX)
     The enzyme the gene CYFIP2 produces when functioning normally is involved in many metabolic pathways in the body including one that plays a role in myelination of nerve cells and one in phospholipid metabolism. (I.13.reuters) (I.14.genecards.CYFIP2)
     So an external source of cannabinoids might help a person with a problem in their CYFIP2 gene to have normal appetite control and also to protect their nerves from multiple sclerosis – which causes degeneration of myelin.  Myelin is similar to the lipid part of some of the phospholipids of the endogenous cannabinoid system. Multiple sclerosis has been associated with social anxiety and eating disorders (I.15.omicsgroup) which are also conditions associated with gene differences in the cannabinoid system. Myelin is made with sphingomyelin which is made of sphingolipids. (I.16.sphingolipids) Easy right? (I.17.mpcfaculty.lipids) Even easier – coconut oil is about 50% phospholipids and is a good source of sphingolipids. (I.18.coconut)
     I don’t know if I have any differences in my CYFIP2 gene; it was not one of the 30 genes that were included in the Nutrigenomic Screening I had done for my personal use for the “purposes of research.” Genetic screening is only used for certain conditions in standard health care currently and some types of health care claims can not be made by practitioners about genetic screening for other conditions – no guarantees in life or lab tests. The screening I had was designed to test genes commonly found to have differences associated with autism. (I.33.Nutrigenomic Screening) (p22, I.34.example of the genetic screening I had)
     I have a genetic difference in my ability to phosphorylate (I.2.wikigenes.BHMT) The gene I have a double malfunction in, BHMT, is also associated with multiple sclerosis except it seems to be with an over activity rather than too little function. Methionine and homocysteine metabolism and vitamin B12 may be involved. (I.19.BMHT.MS) Hypothyroidism may be associated with over expression of this gene: (I.20.wikigenes)
     The enzyme BHMT/1 (Call – T), Betaine-homocysteine methyltransferase (BHMT), in normal health helps produce the amino acids methionine and Dimethylglycine (DMG).
     DMG has been found helpful in ADHD, autism, allergies, alcoholism drug addiction, and chronic fatigue syndrome among other chronic issues. Methionine has been found helpful in treating depression, allergies, alcoholism and schizophrenia among other chronic issues. Since learning of the difference in my genetics I have been taking the two amino acids in a powder form that I add to a glass of water. It doesn’t taste good but it leaves me feeling more energetic and with a more positive mood.
     What it tasted most like was a tart red wine and the nutrient content of red wine does contain free amino acids, so someone with a problem with the BHMT gene may have problems with unidentified cravings that wine seem to help. While I did love red wine, it didn’t love me. It was one of the first triggers for severe migraines that I identified and started avoiding. A painkiller did help with migraine pain somewhat but zero time spent with a migraine is my goal.
     I found based on the information that is available regarding dose, that a half teaspoon of each of the amino acid powders helped my mood without causing such an energy boost that it caused an increased heart rate or prevented me from going to sleep. I tried one teaspoon of each initially and found that it was too much of an energy boost. Both amino acids can act as activating chemicals within the brain.
     I have early symptoms of neuropathy, I would rather prevent multiple sclerosis than to learn more about it first hand. Taking the supplemental methionine may be helping my body do what it needs to do to prevent an autoimmune breakdown of my myelin.

4. Sometimes people are wrong – Nixon was wrong.

If the good people, in their wisdom, shall see fit to keep me in the background, I have been too familiar with disappointments to be very much chagrined.” – Abraham Lincoln (1809-1894), (p 634, I.23)
Hemp fiber was essential for rope and strong fabric. Thomas Jefferson grew hemp and is said to have smoked it too. It is time to stop being disappointed in loved ones who are likely suffering from a metabolic deficiency that leaves them susceptible to substance abuse or overeating and instead start accepting that they have needs that a person of average health doesn’t have or may not have to the same extent. Many nutrients are needed in a just right amount, not too little or too much.
     Cannabinoids are powerful and can be consumed in excess however it does not have the toxicity and deadliness of many other substances that are abused, including alcohol.
     The American Medical Association has recommended that marijuana be rescheduled as an herb with medicinal benefits. (I.24.AMA resolution) (I.25.veteransformedicalmarijuana)
     Rescheduling marijuana as a medicinal plant would free academic researchers to study its medicinal benefits. As a “Scheduled Substance” currently research studies are only supposed to assess toxicity and rehabilitation areas rather than design experiments assessing the medicinal value. Currently the synthetic form of the main euphoric cannabinoid, THC, is listed at a “safer” level of risk than the marijuana plant itself.
     The synthetic forms can be even more dangerous as they are more concentrated and are in isolation rather than also providing the non-euphoric cannabinoids that are found in most strains of marijuana and which have calming effects. Synthetic THC or THC in excess can cause paranoia and other mood symptoms that would have been unknown to Thomas Jefferson when he enjoyed smoking marijuana that was milder in the amount of THC it likely contained and more likely to be balanced with non-euphoric cannabinoids.
     The problem with black market development of a product is that it is often being designed to maximize the “buzz” or “euphoria” rather than the medicinal or pain killing effects. However, there is not that much “euphoria” felt by the person with chronic illness who is using a larger quantity of marijuana everyday due to an underlying inability to make cannabinoids because a tolerance is built up and they simply need some of the herb or other concentrated sources of cannabinoids every day just to maintain a state of health and function that is a little closer to everyone else’s “normal function“.    

     The person with a chronic need wants an herbal medicine that has a balanced variety of cannabinoids that treats a variety of symptoms, not just the euphoria inducing THC that can lead to overdose symptoms of a racing heart, feeling very chilled, and paranoia or anger combined with extra energy, so manic behavior might be a risk with an overdose reaction. Real lime or lemon juice products that are concentrated rather than being a watery lemonade may help counteract some of the mood changes associated with an overdose of THC. More on lemon oil is included in the next section. 

5. Medical Marijuana helps reduce opioid use, which can save lives.

     We currently have an epidemic of deaths due to opioid medications, prescription and black market drugs. The increase in deaths is due in part to the over prescription of opioid painkillers by the medical community but it is also due to black market substitutes that have been introduced in recent years. One type is particularly potent and is being sold as something else so consumers wouldn’t even know that they were being given a stronger version of an opioid medication than the prescription medication they were told they were purchasing on the black market – key point – don’t buy drugs on the black market because you don’t know what they might contain.
     This likely seems an obvious point which, honestly, even the drug addict knows that but their need is great enough during withdrawal that they may be more likely to take risks.
     Women may be especially at risk for opioid addiction whether it is due to differences in size or physiology is unknown. Addiction to opioids seems to occur for women at lower doses of the medication that were taken for a shorter amount of time than for men who become addicted. Women may be more susceptible to the cravings for the drug. (I.27.jotopr)
     In states with medicinal marijuana sales of painkillers dropped,which would include the opioids. Physicians are not comfortable with the inability to “prescribe” a set dose. “Take two hits and call me in the morning?” was asked in jest or in seriousness by a psychiatry professor, Deepak D’Souza, who also has researched marijuana. (I.28.npr)
     Deaths due to overdoses of opioids have also decreased in those states. (I.29.nbcnews) The cannabinoid and opioid receptor systems may both be involved in the regulation of appetite. Levels of the hormone leptin may be increased in response to CB1 receptors in the hypothalamus. Leptin and other appetite hormones may then “control opioid-regulated feeding…(Verty et al., 2003).” See Ch.13: Behavioral Effects of Endocannabinoids, (p313, I.10.Endocannabinoids.Full Text.pdf).
     Since marijuana use seems to be saving lives and has low toxicity risks, it doesn’t seem like how big a dose is as big a question as how to get a safe reliable supply to more patients in pain. The answer does exist but it is one a physician or psychiatrist is unlikely to like – the dose varies based on the person’s genetics and metabolism, the supply of nutrients available, tolerance, etc.; the answer is “It depends.” But the medication is so safe that worries about “too much” are really unnecessary, except possibly for more concentrated synthetic sources or extracted cannabinoid oil products.
     Signs of “too much” THC or synthetic THC can include a racing heartbeat, which very, very rarely has caused a couple/very few deaths. To the user first experiencing the racing heartbeat of excess THC, it may be frightening and feel like a panic attack. Relax it slows down again and only people with a pre-existing heart condition may be at risk during the time that the heart-rate is rapid.
     So if you have a weak heart – avoid excessive amounts of THC. The rapid heart-rate doesn’t occur at low doses. It may be accompanied a feeling of being chilled, and suddenly needing a jacket. Anxiety or anger may occur with excess THC or synthetic THC or during withdrawal from an excessive amount.
     The aromatic terpenes in citrus oil can have a calming effect if anxiety is a problem after consuming marijuana. Pinene from pistachio nuts may also be helpful, but a glass of lemonade might help the mood more quickly than eating pistachios because they would take longer to digest. (I.26.fastcompany)
     Artificial lemon flavored products wouldn’t help, only real lemon or lime juice products would help calm a mood unsettled by an excess or imbalance of THC. The plant contains many active phytochemicals which can include terpenes and other cannabinoids that are calming to the mood rather than causing euphoria. THC is the only cannabinoid in marijuana that causes euphoria.
     Opioid medications also cause euphoria – so why is one more socially acceptable than the other? Smoking is dirty and smelly and – the easiest way to not overdose.
     Eating products or the concentrated synthetic dose in one single sitting can leave a person feeling symptoms of overdose about one hour later, far too late to stop at half a serving or a small taste to see how you might handle that particular product and/or the strain that was used in it. Different strains of the plant can cause very different symptoms and help different types of symptoms, so the question of “how much” is less significant than which strain to use and the method to use to consume it.
     Smoking provides fairly instant changes to the mood so it is easy to tell if you’re getting more anxious or developing a rapid heart rate. Strains of marijuana can vary a lot, some types may cause the anxiety symptoms, while others would just cause the stereotypical “couchlock” – falling asleep. While setting fire to the couch might be a very real risk, otherwise, no danger other than possibly drooling a little and looking stupid. Looking stupid is better than looking dead from an opioid overdose – in my opinion – and I am a medical marijuana patient who has experienced these symptoms and read research about safe use.

6. Resources for help or just someone to talk to:

  • National Helpline: Substance Abuse and Mental Health Services Administration: “SAMHSA’s National Helpline, 1-800-662-HELP (4357), (also known as the Treatment Referral Routing Service), is a free, confidential, 24/7, 365-day-a-year treatment referral and information service (in English and Spanish) for individuals and families facing mental and/or substance use disorders.” (1.30samhsa.org)
  • Rape, Abuse and Incest National Network, RAINN Hotline: 1-800-656-HOPE, (1.31RAINN.)
  • U.S. National Suicide Prevention Hotline: “Call 1-800-273-8255, Available 24 hours everyday.” (1.32.suicidepreventionlifeline.org)

Help is only helpful when you accept it. Recognizing that you need it is the first step.

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.

Links and References:

(I’ll finish this list later, I’ve learned a lazy editing tactic is to skip the footnote numbers until the final draft is complete.)

  1. Disease,” Oxford Dictionaries (I.1.disease)
  2. BHMT,” wikigenes.org, http://www.wikigenes.org/e/gene/e/635.html (I.wikigenes.BHMT)
  3. Glycerophospholipid biosynthesis,
  4. metabolism ,
  5. Phospholipid metabolism,
  6. (I.6.genecards.BHMT) [http://www.genecards.org/cgi-bin/carddisp.pl?gene=BHMT] (I.6.genecards.BHMT)
  7. (I.7.genecards.phosphorylation) [http://pathcards.genecards.org/card/cdk-mediated_phosphorylation_and_removal_of_cdc6] (I.genecards.phosphorylation)
  8. Leukotriene,” (I.8.scbt.com)
  9. Behavioral Neurobiology of the Endocannabinoid System; Ch.13: Drug Addiction, (page 334, I.9.Searchworks)  Behavioral Neurobiology of the Endocannabinoid System, Editors David Kendall and Stephen Alexander (Springer, 2009, Nottingham, U.K.). (I.Searchworks)
  10. Endocannabinoids: The Brain and Body’s Marijuana and Beyond, (CRC Press, 2006, Boca Raton, FL), Chapter Three, Endocannabinoid Receptor Genetics and Marijuana Use, editor and chapter by Emmanuel S. Onaivi, et al., (pages 72-73, 91, and 333), Chapter 15, Neuropsychiatry: Schizophrenia, Depression, and Anxiety, chapter by Ester Fride and Ethan Russo, (page 378), (I.10.Endocannabinoids: FullText pdf)
  11. (I.11.sciencedaily) Genetic risk factor for binge eating discovered. Sciencedaily.com, Oct. 26, 2016,  https://www.sciencedaily.com/releases/2016/10/161026170543.htm (I.sciencedaily)
  12. (I.12.ncbi.FragileX) Sabiha Abekhoukh and Barbara Bardoni, CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome, Front Cell Neurosci. 2014; 8: 81., ncbi.nlm.nih.gov https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3973919/ (I.ncbi.FragileX)
  13. (I.13.reuters) Pathway Maps: G-protein signaling_RAC1 in cellular process, Life Sciences Research, thomsonreuters.com, http://lsresearch.thomsonreuters.com/maps/383 (I.reuters)
  14. (I.14.genecards.CYFIP2) CYFIP2, genecards.org,  http://www.genecards.org/cgi-bin/carddisp.pl?gene=CYFIP2 (I.genecards.CYFIP2)
  15. (I.15.omicsgroup) Shahla Mohamadirizi1*, Vahid Shaygannejad2, Soheila Mohamadirizi3 and Marjan Mohamadirizi4, Eating disorders in a multiple sclerosis clinical population and its association with social anxiety.   https://www.omicsgroup.org/journals/eating-disorders-in-a-multiple-sclerosis-clinical-population-and-its-associationwith-social-anxiety-2376-0389-1000183.php?aid=82623 (I.omicsgroup)
  16. (I.16.sphingolipids)
  17. (I17..mpcfaculty.lipids)
  18. (I.18.coconut) Handbook of Plant-Based Fermented Food and Beverage Technology, Second Edition, edited by Y. H. Hui, E. Özgül Evranuz  CRC Press, May 17, 2012, https://books.google.com/books?id=5fvRBQAAQBAJ&pg=PA669&lpg=PA669&dq=sphingolipids+in+coconut&source=bl&ots=QlgC46XLn8&sig=Y5AiDM4oUTBp9BS3aOKCtWK0Fbk&hl=en&sa=X&ved=0ahUKEwiQuL-wmdbVAhUG7CYKHXZCCxsQ6AEILjAB#v=onepage&q=sphingolipids%20in%20coconut&f=false
  19. (I.19.BMHT.MS) Naveen Kumar Singhal, et al., Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis. J of Neuroscience Vol 35, Issue 45, 2015 PAGES: 15170-15186 ISSN: 0270-6474 https://www.researchgate.net/profile/Rohan_Dassanayake2/publication/283710653_Changes_in_Methionine_Metabolism_and_Histone_H3_Trimethylation_Are_Linked_to_Mitochondrial_Defects_in_Multiple_Sclerosis/links/5693c64508aeab58a9a2aaf3.pdf (I.BMHT.MS)
  20. (I.20.wikigenes)
  21. ( methionine )
  22. ( Dimethylglycine (DMG).
  23. John Bartlett, Familiar Quotations, 14th Ed., 1910, (p 634, I.23)
  24. (I.24.AMA resolution) American Medical Association Medical Student Section, Resolution 2, JUne 8, 2008, http://www.oregon.gov/pharmacy/Imports/Marijuana/Public/AMA_MedStudentSectionResolution.pdf (I.AMA resolution)
  25. (I.25.veteransformedicalmarijuana) AMA Votes to Reschedule Medical Marijuana, VMCA, http://www.veteransformedicalmarijuana.org/node/67 (I.veteransformedicalmarijuana)
  26. (I.26.fastcompany) Chris Dannen, Three Beginner Mistakes to Avoid When Eating Cannabis, fastcompany.com Sept. 10, 2014, https://www.fastcompany.com/3035175/three-beginner-mistakes-to-avoid-when-eating-cannabis (I.fastcompany)
  27. (I.27.jotopr) Karen Barth, New Study Shows Women are Hit the Hardest as Opioid Epidemic Sweeps the Country. Jotopr.com, Feb. 27, 2017, https://jotopr.com/new-study-shows-women-are-hit-hardest-as-opioid-epidemic-sweeps-the-country/?utm_source=ReviveOldPost&utm_medium=social&utm_campaign=ReviveOldPost (I.jotopr)
  28. (I.28.npr) Shefali Luthra, After Medical Marijuana Legalized, Medicare Prescriptions Drop for Many Drugs. npr.org, July 6, 2016, http://www.npr.org/sections/health-shots/2016/07/06/484977159/after-medical-marijuana-legalized-medicare-prescriptions-drop-for-many-drugs (I.npr)
  29. Reuters, Legalized Marijuana Could Help Curb the Opioid Epidemic, Study Finds. March 27, 2017,nbcnews.com,  http://www.nbcnews.com/health/health-news/legalized-marijuana-could-help-curb-opioid-epidemic-study-finds-n739301 (I.29.nbcnews)
  30. National Helpline: Substance Abuse and Mental Health Services Administration: 1-800-662-HELP (4357), (1.30samhsa.org)
  31. Rape, Abuse and Incest National Network, RAINN Hotline: 1-800-656-HOPE, (1.31RAINN.)
  32. U.S. National Suicide Prevention Hotline:  1-800-273-8255, (1.32.suicidepreventionlifeline.org)
  33. Amy Yasko, Nutrigenomic Testing, Holistic Health International, http://www.holisticheal.com/health-tests/nutrigenomic-testing (I.33.Nutrigenomic Screening)
  34. Amy Yasko, Methylation Analysis Pathway: John Doe, Neurological Research Institute, http://www.holisticheal.com/media/wysiwyg/John_Doe_MPA_05.19.17.pdf (p22, I.34.example of the genetic screening I had)

World Autism Awareness Day; “Please teacher” video

It is World Autism Awareness Day and this video of children with autism addressing their teachers is heart breaking – and hopeful.

 

Recently I was reading a poem by someone with autism and it reminded me of me. It was describing a feeling of not fitting in with the normal types of people but not wanting to be lumped in with the type of people who couldn’t communicate at all:

High functioning people with autism might understand and listen and be interested but not be comfortable or able to speak their thoughts well. They might enjoy going to a party and just listening and smiling on the outskirts rather than chatting much but they could still be enjoying themselves in their own ways. I liked to water plants during social gatherings at a church where I was a member. I was part of the group and enjoyed saying hi’s briefly to people and it helped the plants and gave me something to do so it wouldn’t seem odd to not get into longer chats with people. I’m much better at talking about nutrition then about social chit-chat.

Some families have found that smartphones allow instant texting as a modern solution to conversation. The family talks and the person with autism listens and texts back to them in response. It can also be common for people with autism to communicate in snippets of quoted lyrics or other phrases – using other’s words to say what’s also on their mind.

The Legoland article reminded me of my favorite “amusement” museum. The City Museum in St. Louis, Missouri is full of decorations made from recycled materials built into mosaics and patterned walls. The museum is built within and on the grounds of a large multi-storied building that was a shoelace factory. Shoelaces are still made there and can be purchased. There are numerous imaginative landscapes that can be physically explored and played on and in and under and above – the place is a jungle and cavern and a maze and amazing – truly. If I could live anywhere on the planet that I wanted to, then it might be here: http://www.citymuseum.org/

Disclaimer: Opinions are my own and the information is provided for educational purposes within the guidelines of fair use. While I am a Registered Dietitian this information is not intended to provide individual health guidance. Please see a health professional for individual health care purposes.